Date published: 2026-4-1

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tert-Butyl bicyclo[2.2.2]phosphorothionate (CAS 70636-86-1)

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Alternate Names:
TBPS
Application:
tert-Butyl bicyclo[2.2.2]phosphorothionate is a GABAA receptor antagonist
CAS Number:
70636-86-1
Molecular Weight:
222.24
Molecular Formula:
C8H15O3PS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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tert-Butyl bicyclo[2.2.2]phosphorothionate is a compound of interest in a variety of research applications, especially in the field of organic chemistry where it is often used as a reagent. It has been utilized in studies focusing on the synthesis of organophosphorus compounds, which are important in the development of novel organic molecules with potential applications in materials science. The unique structure of tert-Butyl bicyclo[2.2.2]phosphorothionate, featuring a bicyclic phosphorothioate moiety, allows researchers to explore its reactivity and use in constructing more complex molecular architectures. Additionally, the compound is used as a starting material in the synthesis of ligands for transition metals, contributing to research on coordination chemistry and catalysis. Its role in the synthesis of sulfur-containing heterocycles is also notable, as such compounds are of interest for their potential utility in various industrial applications.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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tert-Butyl bicyclo[2.2.2]phosphorothionate (CAS 70636-86-1) References

  1. Trimethylolpropane phosphate induces epileptiform discharges in the CA1 region of the rat hippocampus.  |  Lin, J., et al. 2001. Toxicol Appl Pharmacol. 171: 126-34. PMID: 11222088
  2. Binding characteristics of [3H]ucb 30889 to levetiracetam binding sites in rat brain.  |  Gillard, M., et al. 2003. Eur J Pharmacol. 478: 1-9. PMID: 14555178
  3. Biologic activity of cyclic and caged phosphates: a review.  |  Lorke, DE., et al. 2017. J Appl Toxicol. 37: 13-22. PMID: 27612208
  4. Pharmacological properties of T-type Ca2+ current in adult rat sensory neurons: effects of anticonvulsant and anesthetic agents.  |  Todorovic, SM. and Lingle, CJ. 1998. J Neurophysiol. 79: 240-52. PMID: 9425195
  5. Repeated exposure to trimethylolpropane phosphate induces central nervous system sensitization and facilitates electrical kindling.  |  Lin, J., et al. 1998. Physiol Behav. 65: 51-8. PMID: 9811364

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

tert-Butyl bicyclo[2.2.2]phosphorothionate, 2 mg

sc-253633
2 mg
$444.00