Molecular structure of TCO-NHS ester, CAS Number: 1191901-33-3
TCO-NHS ester (CAS 1191901-33-3)
Alternate Names:
Trans-Cyclooctene (TCO)-NHS Ester; TCO-Carbonate; (E)-Cyclooct-4-enyl-2,5-dioxo-1-pyrrolidinyl carbonate
Application:
TCO-NHS ester is an amine-reactive building block used to derivatize primary amine-containing molecules with a TCO moiety
CAS Number:
1191901-33-3
Molecular Weight:
267.28
Molecular Formula:
C13H17NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
TCO-NHS ester is an amine-reactive building block used to derivatize primary amine-containing molecules with a TCO moiety. TCO-NHS ester reacts specifically and efficiently with a primary amine (e.g., side chain of lysine residues or aminosilane-coated surfaces) at pH 7-9 to form a covalent bond. Short spacer arm adds minimal mass to modified molecules (153.2 daltons). Applications include protein-protein conjugation, protein-antibody conjugation, protein-small molecule conjugation, 18F radiolabeling, protein-oligonucleotide conjugation, and surface modification.
TCO-NHS ester (CAS 1191901-33-3) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TCO-NHS ester, 25 mg | sc-498419 | 25 mg | $297.00 | |||
TCO-NHS ester, 100 mg | sc-498419A | 100 mg | $883.00 | |||
TCO-NHS ester, 1 g | sc-498419B | 1 g | $3830.00 |