Tastin Antibody (H-1): sc-373714
- Tastin Antibody (H-1) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 3-232 mapping near the N-terminus of Tastin of mouse origin
- Anti-Tastin Antibody (H-1) is recommended for detection of Tastin of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Tastin Antibody (H-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Tastin Antibody (H-1). This work is in progress.
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SEE ALSO...
Tastin Antibody (H-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects Tastin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Tastin (H-1) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Tastin, also known as trophinin associated protein (TROAP), plays a critical role in maintaining centrosome integrity and ensuring proper bipolar organization of the mitotic spindle during cell division. Tastin localization in the cytoplasm is vital, as Tastin associates with microtubules, the mitotic spindle, and centrosomes, which are essential for accurate chromosome segregation. Tastin expression peaks during the G2/M phase of the cell cycle, highlighting Tastin′s importance in cell proliferation, and declines post-mitosis. Notably, cells that overexpress Tastin tend to form monopolar spindles, while those with depleted levels exhibit multipolar spindles, indicating Tastin′s crucial role in spindle assembly. Tastin also interacts with key proteins such as Dynein light chain (Tctex-1) and γ Tubulin, further underscoring Tastin′s involvement in the dynamics of cell division. Additionally, Tastin forms complexes with Bystin and Trophinin, which are important for cell adhesion and embryo implantation, emphasizing Tastin′s multifaceted role in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tastin Antibody (H-1) | sc-373714 | 200 µg/ml | $322.00 | |||
Tastin Antibody (H-1) AC | sc-373714 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Tastin Antibody (H-1) HRP | sc-373714 HRP | 200 µg/ml | $322.00 | |||
Tastin Antibody (H-1) FITC | sc-373714 FITC | 200 µg/ml | $336.00 | |||
Tastin Antibody (H-1) PE | sc-373714 PE | 200 µg/ml | $349.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 488 | sc-373714 AF488 | 200 µg/ml | $364.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 546 | sc-373714 AF546 | 200 µg/ml | $364.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 594 | sc-373714 AF594 | 200 µg/ml | $364.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 647 | sc-373714 AF647 | 200 µg/ml | $364.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 680 | sc-373714 AF680 | 200 µg/ml | $364.00 | |||
Tastin Antibody (H-1) Alexa Fluor® 790 | sc-373714 AF790 | 200 µg/ml | $364.00 |