CD138/SDC1/Syndecan-1 Antibody (2Q1484): sc-73094

Syndecan-1 Antibody (2Q1484) is a mouse monoclonal IgG1 antibody that detects Syndecan-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Syndecan-1, also known as CD138, is a type I integral membrane proteoglycan that plays a crucial role in cell signaling and adhesion by serving as a receptor for the extracellular matrix. Syndecan-1 (2Q1484) antibody recognizes protein expression on the basolateral surfaces of epithelial cells, endothelial cells of sprouting capillaries, and embryonic condensing mesenchymal cells, highlighting its importance in tissue development and repair. Anti-Syndecan-1 antibody (2Q1484) detects interactions with various extracellular matrix components, including collagens, fibronectin, and thrombospondin, which are essential for maintaining tissue architecture and facilitating cellular communication. Syndecan-1 monoclonal antibody (2Q1484) reveals co-localization with actin-rich filaments, suggesting a role in linking the cytoskeleton to the extracellular matrix, thereby influencing cell shape, motility, and overall cellular function. This multifaceted involvement in cellular processes makes Syndecan-1 a significant target for research in developmental biology and cancer studies, where expression patterns can provide insights into disease mechanisms and potential therapeutic strategies.

The preferred CD138/SDC1/Syndecan-1 antibody is CD138/SDC1/Syndecan-1 Antibody (DL-101): sc-12765.