Sulforhodamine 101 CAS: 60311-02-6
MF: C31H30N2O7S2
MW: 606.71
A red-emitting flurophore used to label astrocytes.

Sulforhodamine 101 (CAS 60311-02-6)

Sulforhodamine 101 | CAS 60311-02-6 is rated 5.0 out of 5 by 1.
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Application: Sulforhodamine 101 is a red-emitting flurophore used to label astrocytes
CAS Number: 60311-02-6
Purity: ≥98%
Molecular Weight: 606.71
Molecular Formula: C31H30N2O7S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sulforhodamine 101 is a red emitting fluorophore with an extinction coefficient of 105000. Sulforhodamine 101 is ideally used to label astrocytes in the rodent neocortex which can be observed with two-photon microscopy. In addition, Sulforhodamine 101 is used to determine morphological characteristics of astrocytes and to observe the association of astrocytes with the cortical microvasculature. Furthermore, this fluorophore is used as an activity-dependent dye for monitoring regulated exocytosis. Alternate studies suggest that Sulforhodamine 101 can increase intrinsic neuronal excitability and long-lasting increases in evoked EPSCs in CA1 pyramidal neurons in hippocampal slices. Sulforhodamine 101 enhances evoked synaptic N-methyl D-aspartate receptor (NMDAR) currents which can be blocked by the antagonist, AP-5.


References

1. Nimmerjahn, A., et al. 2004. Nat. Methods. 1: 31-37. PMID: 15782150
2. Kang, J., et al. 2010. Neuroscience. 169: 1601-1609. PMID: 20600669

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (partly), methanol (1 mg/ml), DMSO, and DMF.
Storage :
Store at room temperature
Fluoresence :
λex 582-588 nm, λem 601-609 nm in Buffer pH 7; λex 586 nm, λem 605 nm in H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
122180
MDL Number :
MFCD00012407
EC Number :
262-159-4
Beilstein Registry :
3582548
SMILES :
C1CC2=C3C(=C4C(=C2)C(=C5C=C6CCC[N+]7=C6C(=C5O4)CCC7)C8=C(C=C(C=C8)S(=O)(=O)O)S(=O)(=O)[O-])CCCN3C1

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Sulforhodamine 101 (CAS 60311-02-6) Product Citations

See how others have used Sulforhodamine 101 (CAS 60311-02-6). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 31696993  Glia.

PMID: # 31506300  J. Biol. Chem. 294: 16034-16048.

PMID: # 30883940  Glia. 67: 1385-1400.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from Various publications cite the use of Sulforhodamine Various publications cite the use of Sulforhodamine 101 to label astrocytes in the rodent neocortex which can be observed with two-photon microscopy. In addition, Sulforhodamine 101 is used to determine morphological characteristics of astrocytes and to observe the association of astrocytes with the cortical microvasculature. -SCBT Publication Review
Date published: 2015-05-20
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