Sprouty 1 Antibody (RR-15): sc-100861

Sprouty 1 Antibody (RR-15) is a mouse monoclonal IgG2a antibody that detects Sprouty 1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Sprouty 1 plays a crucial role as a negative regulator of growth factor signaling, particularly in the context of fibroblast growth factor (FGF) and vascular endothelial growth factor (VEGF) pathways, which are essential for processes such as cell proliferation and angiogenesis. Sprouty 1 is primarily localized in the cytoplasm and can translocate to the plasma membrane upon activation, where Sprouty 1 interacts with key signaling molecules to modulate cellular responses. This dynamic localization is vital for function, as Sprouty 1 effectively inhibits excessive cell growth and migration, thereby maintaining tissue homeostasis and preventing pathological conditions such as cancer. Additionally, Sprouty 1 undergoes post-translational modifications, including phosphorylation, which can influence activity and interactions with other proteins, further underscoring importance in cellular signaling networks. With an ability to regulate critical growth factor pathways, Sprouty 1 is a significant player in developmental processes and disease mechanisms, making anti-Sprouty 1 antibody (RR-15) an invaluable tool for researchers studying these complex biological systems.

The preferred Sprouty 1 antibody is Sprouty 1 Antibody (H-2): sc-365520.