SIRT2 Inhibitor, Inactive Control (CAS 304896-21-7)
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SIRT2 Inhibitor, Inactive Control, also known as AGK7, is a cell-permeable structural isomer of SIRT2 (sirtuin 2) Inhibitor, AGK2 (sc-202813) that selectively inhibits SIRT3 over SIRT1 and SIRT2 (IC50 = >5 muM, >50 muM and >50 muM for SIRT3, SIRT1 and SIRT2, respectively). SIRT2 Inhibitor, Inactive Control poorly affects both alpha-synuclein-mediated toxicity and alpha-Syn aggregation in alpha-Syn-H4 cells. It is also an inhibitor of SIRT1 (sirtuin 1) and SIRT3 (sirtuin 3). In catalysis, it exhibits high activity and selectivity in various reactions such as oxidation, reduction, and cross-coupling reactions. In gas storage, the compound has a high adsorption capacity for gases such as hydrogen, methane, and carbon dioxide.
SIRT2 Inhibitor, Inactive Control (CAS 304896-21-7) References
- Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. | Outeiro, TF., et al. 2007. Science. 317: 516-9. PMID: 17588900
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SIRT2 Inhibitor, Inactive Control, 5 mg | sc-204281 | 5 mg | $255.00 |