Molecular structure of Sialorphin, CAS Number: 131748-26-0
Sialorphin (CAS 131748-26-0)
CAS Number:
131748-26-0
Molecular Weight:
650.69
Molecular Formula:
C26H42N12O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An analgesic and an exocrine and endocrine signaling mediator, predominantly synthesized in the submandibular gland and prostate of adult rats. Sialorphin prevents spinal and renal NEP from breaking down substance P and Met-enkephalin in vitro. It inhibits the breakdown of substance P with an IC50 of 0.4-1 µM and behaves as a competitive inhibitor. Elicits potent antinociceptive responses in two behavioral rat models of injury-induced acute and tonic pain. Has a role in erectile function most likely through a mechanism that involves relaxation of corporal smooth muscle tissue.
Sialorphin (CAS 131748-26-0) References
Rougeot, C., et al., , Sialorphin, a natural inhibitor of rat membrane-bound neutral endopeptidase that displays analgesic activity. Proc. Natl. Acad. Sci. U. S. A. 100, 8549-8554, (2003)Inhibitor of:
Neprilysin-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sialorphin, 1 mg | sc-253554 | 1 mg | $237.00 |