Date published: 2026-2-2

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SC9 (CAS 102649-78-5)

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Application:
SC9 is a Protein kinase C (PKC) activator in the presence of Ca2+
CAS Number:
102649-78-5
Purity:
98%
Molecular Weight:
402.0
Molecular Formula:
C22H24CINO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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SC-9 is a PKC (protein kinase C) activator in the presence of Ca2+.


SC9 (CAS 102649-78-5) References

  1. Neurokinin3 receptor regulation of acetylcholine release from myenteric plexus.  |  Yau, WM., et al. 1992. Am J Physiol. 263: G659-64. PMID: 1279982
  2. Manipulation of phototransductive membrane turnover by crab photoreceptors in vitro: effects of two protein kinase activators, SC-9 and phorbol ester in the presence of a protein phosphatase inhibitor, okadaic acid.  |  Blest, AD., et al. 1992. J Comp Physiol A. 170: 189-99. PMID: 1316437
  3. Activation and inhibition of protein kinase C in cultured bovine parathyroid cells: effect on the release of C-terminal fragments of parathyroid hormone.  |  Watson, PH., et al. 1992. J Bone Miner Res. 7: 667-74. PMID: 1414485
  4. Regulation of acrosome reaction of fowl spermatozoa: evidence for the involvement of protein kinase C and protein phosphatase-type 1 and/or -type 2A.  |  Ashizawa, K., et al. 2006. Reproduction. 131: 1017-24. PMID: 16735541
  5. Evidence for the involvement of protein kinase C in the modulation of morphine-induced 'analgesia' and the inhibitory effects of exposure to 60-Hz magnetic fields in the snail, Cepaea nemoralis.  |  Kavaliers, M., et al. 1991. Brain Res. 554: 65-71. PMID: 1933319
  6. Egr-1 expression in surface Ig-mediated B cell activation. Kinetics and association with protein kinase C activation.  |  Seyfert, VL., et al. 1990. J Immunol. 145: 3647-53. PMID: 2246508
  7. Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.  |  Couldwell, WT., et al. 1990. J Neurosurg. 73: 594-600. PMID: 2398390
  8. Purification of a protein C activator from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix).  |  Klein, JD. and Walker, FJ. 1986. Biochemistry. 25: 4175-9. PMID: 3530318
  9. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C.  |  Ito, M., et al. 1986. Biochemistry. 25: 4179-84. PMID: 3756133
  10. N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase.  |  Nishino, H., et al. 1986. Biochim Biophys Acta. 889: 236-9. PMID: 3778949
  11. Effects of activators (SC-9 and OAG) and inhibitors (staurosporine and H-7) of protein kinase C on the proliferation of mouse epidermal melanoblasts in serum-free culture.  |  Hirobe, T. 1994. J Cell Sci. 107 (Pt 6): 1679-86. PMID: 7962208
  12. Possible role of protein kinase C in regulation of flagellar motility and intracellular free Ca2+ concentration of fowl spermatozoa.  |  Ashizawa, K., et al. 1994. J Reprod Fertil. 101: 511-7. PMID: 7966004
  13. Activation of protein kinase C in human hepatocellular carcinoma (HEP3B) cells increases erythropoietin production.  |  Yoshioka, K., et al. 1998. Life Sci. 63: 523-35. PMID: 9718078

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

SC9, 1 mg

sc-202336
1 mg
$30.00

SC9, 5 mg

sc-202336A
5 mg
$64.00

SC9, 50 mg

sc-202336B
50 mg
$560.00