Date published: 2026-4-26

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(S)-Lofexidine (CAS 81447-79-2)

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Alternate Names:
2-[(1S)-1-(2,6-Dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole; (-)-Lofexidine; Dexlofexidine
CAS Number:
81447-79-2
Molecular Weight:
259.13
Molecular Formula:
C11H12Cl2N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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The S-enantiomer of Lofexidine and a α2-Adrenoceptor agonist related structurally to Clonidine. It is used in the treatment of opioid withdrawal symptoms and is anti-hypertensive.


(S)-Lofexidine (CAS 81447-79-2) References

Velly, J., et al.: J. Pharmacol., 8, 351 (1977), Jarrot, B., et al.: Biochem. Pharmacol., 28, 141 (1979), Birch, P., at al.: Brit. J. Pharmacol., 68, 107 (1980),

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(S)-Lofexidine, 1 mg

sc-212885
1 mg
$280.00

(S)-Lofexidine, 2 mg

sc-212885A
2 mg
$575.00