Molecular structure of (S)-ATPA, CAS Number: 83654-14-2
(S)-ATPA (CAS 83654-14-2)
Alternate Names:
(S)-α-Amino-3-hydroxy-5-t-butyl-4-isoxazolepropionic acid
Application:
(S)-ATPA is a GluR-5 kainate receptor agonist
CAS Number:
83654-14-2
Molecular Weight:
228.25
Molecular Formula:
C10H16N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(S)-ATPA, the active enantiomer of 2-Amino-3-[3-hydroxy-5-tert-butylisoxazol-4-yl]propanoic acid (ATPA), is a potent and selective agonist of the GluR-5 kainate receptor.
(S)-ATPA (CAS 83654-14-2) References
- Resolution, absolute stereochemistry and molecular pharmacology of the enantiomers of ATPA. | Stensbøl, TB., et al. 1999. Eur J Pharmacol. 380: 153-62. PMID: 10513575
- Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity. | Lunn, ML., et al. 2003. J Med Chem. 46: 872-5. PMID: 12593667
- Pharmacological profile of the isomers of the GluR-specific agonist ATPA. | Curry, K. and Pajouhesh, H. 1998. Can J Physiol Pharmacol. 76: 690-2. PMID: 9923408
Activator of:
GluR-5.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-ATPA, 1 mg | sc-222280 | 1 mg | $60.00 |