RT-4 Whole Cell Lysate: sc-364257

RT-4 whole cell lysate is derived from the RT-4 cell line, which originates from a human urothelial papilloma and is extensively used in urological cancer research. This lysate is particularly valuable for studying the molecular mechanisms of bladder cancer cell differentiation and the early stages of tumorigenesis in urothelial cells. Researchers employ RT-4 lysate to examine the expression and regulation of genes involved in cell cycle control, apoptosis, and cell adhesioncritical factors in cancer progression and cellular integrity. It facilitates the study of signaling pathways such as the PI3K/Akt pathway, which is known for its role in promoting cell survival and proliferation, and the p53 pathway, important for its tumor suppressor functions. Additionally, RT-4 cell lysate is used to investigate the cellular responses to environmental toxins and chemotherapeutic agents, providing insights into how urothelial cells resist or succumb to such treatments. By analyzing these interactions and responses, RT-4 lysate helps in understanding the unique properties of urothelial papilloma cells. This focus ensures that the insights gained are applicable broadly to the basic science of urological cell biology.