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(RS)-4C3H-PG (CAS 134052-66-7)

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Alternate Names:
(RS)-4-Carboxy-3-hydroxyphenylglycine
Application:
(RS)-4C3H-PG is a broad spectrum EAA ligand
CAS Number:
134052-66-7
Molecular Weight:
211.17
Molecular Formula:
C9H9NO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(RS)-4C3H-PG is a broad spectrum EAA ligand.


(RS)-4C3H-PG (CAS 134052-66-7) References

  1. Pharmacological agents acting at subtypes of metabotropic glutamate receptors.  |  Schoepp, DD., et al. 1999. Neuropharmacology. 38: 1431-76. PMID: 10530808
  2. 4C3HPG (RS-4-carboxy-3-hydroxyphenylglycine), a weak agonist at metabotropic glutamate receptors, occludes the action of trans-ACPD in hippocampus.  |  Gerber, U. and Gähwiler, BH. 1992. Eur J Pharmacol. 221: 401-2. PMID: 1385184
  3. Metabotropic glutamate receptor antagonists selectively enhance responses of slowly adapting type I mechanoreceptors.  |  Cahusac, PM. and Senok, SS. 2006. Synapse. 59: 235-42. PMID: 16385550
  4. Role of metabotropic glutamate receptor subtypes in the patterning of epileptiform activities in vitro.  |  Merlin, LR., et al. 1995. J Neurophysiol. 74: 896-900. PMID: 7472393
  5. Increased perinuclear Ca2+ activity evoked by metabotropic glutamate receptor activation in rat hippocampal neurones.  |  Phenna, S., et al. 1995. J Physiol. 486 (Pt 1): 149-61. PMID: 7562631
  6. Pharmacological analysis of carboxyphenylglycines at metabotropic glutamate receptors.  |  Cavanni, P., et al. 1994. Eur J Pharmacol. 269: 9-15. PMID: 7828660
  7. Phenylglycine derivatives as antagonists of metabotropic glutamate receptors.  |  Watkins, J. and Collingridge, G. 1994. Trends Pharmacol Sci. 15: 333-42. PMID: 7992387
  8. Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes.  |  Hayashi, Y., et al. 1994. J Neurosci. 14: 3370-7. PMID: 8182479
  9. Evidence for a role of metabotropic glutamate receptors in sustained nociceptive inputs to rat dorsal horn neurons.  |  Young, MR., et al. 1994. Neuropharmacology. 33: 141-4. PMID: 8183438
  10. Metabotropic glutamate receptor agonist-induced hyperpolarizations in rat basolateral amygdala neurons: receptor characterization and ion channels.  |  Holmes, KH., et al. 1996. J Neurophysiol. 76: 3059-69. PMID: 8930255

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(RS)-4C3H-PG, 10 mg

sc-203245
10 mg
$200.00

(RS)-4C3H-PG, 50 mg

sc-203245A
50 mg
$739.00