Molecular structure of Rp-8-pCPT-cyclic GMPS Sodium, CAS Number: 153660-04-9
Rp-8-pCPT-cyclic GMPS Sodium (CAS 153660-04-9)
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Application:
Rp-8-pCPT-cyclic GMPS Sodium is a potent, selective PKGα1, 1β and type II inhibitor
CAS Number:
153660-04-9
Purity:
≥98%
Molecular Weight:
525.9
Molecular Formula:
C16H14ClN5O6PS2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
Rp-8-pCPT-cyclic GMPS Sodium is a potent and selective inhibitor of cGMP-dependent protein kinase (PKG) 1alpha, 1beta and type II. The compound is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Rp-8-pCPT-cyclic GMPS Sodium is significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.
Rp-8-pCPT-cyclic GMPS Sodium (CAS 153660-04-9) References
- The type II isoform of cGMP-dependent protein kinase is dimeric and possesses regulatory and catalytic properties distinct from the type I isoforms. | Gamm, DM., et al. 1995. J Biol Chem. 270: 27380-8. PMID: 7593002
- (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. | Butt, E., et al. 1994. Eur J Pharmacol. 269: 265-8. PMID: 7851503
- Mobility of the arm following radical mastectomy. | Degenshein, GA. 1977. Surg Gynecol Obstet. 145: 77. PMID: 877828
Inhibitor of:
Enzyme, PKA, and PKB Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rp-8-pCPT-cyclic GMPS Sodium, 100 µg | sc-202030 | 100 µg | $62.00 | |||
Rp-8-pCPT-cyclic GMPS Sodium, 1 mg | sc-202030A | 1 mg | $265.00 |