Rp-8-pCPT-cyclic GMPS Sodium CAS: 153660-04-9
MF: C16H14ClN5O6PS2•Na
MW: 525.9
A potent, selective PKGα1, 1β and type II inhibitor.

Rp-8-pCPT-cyclic GMPS Sodium (CAS 153660-04-9)

Rp-8-pCPT-cyclic GMPS Sodium | CAS 153660-04-9 is rated 5.0 out of 5 by 1.
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Application: Rp-8-pCPT-cyclic GMPS Sodium is a potent, selective PKGα1, 1β and type II inhibitor
CAS Number: 153660-04-9
Purity: ≥98%
Molecular Weight: 525.9
Molecular Formula: C16H14ClN5O6PS2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Rp-8-pCPT-cyclic GMPS Sodium is a potent and selective inhibitor of cGMP-dependent protein kinase (PKG) 1α, 1β and type II. The compound is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Rp-8-pCPT-cyclic GMPS Sodium is significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.


References

1. Butt, E., et al. 1994. Eur. J. Pharmacol. 269: 265-268. PMID: 7851503
2. Gamm, D.M., et al. 1995. J. Biol. Chem. 270: 27380-273808. PMID: 7593002
3. Kramer, R.H. and Tibbs, G.R. 1996. J. Neurosci. 16: 1285-1293. PMID: 877828

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44755050
SMILES :
C1[[email protected]@H]2[[email protected]]([[email protected]]([[email protected]@H](O2)N3C4=C(C(=O)N=C(N4)N)N=C3SC5=CC=C(C=C5)Cl)O)OP(=S)(O1)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from worked great in our experiments worked great in our experiments.
Date published: 2015-09-01
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