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Rp-8-Br-cGMPS is a synthetic analogue of cyclic guanosine monophosphate (cGMP) and functions as a potent inhibitor of protein kinase G (PKG). This compound is used in various research applications to study the cellular signaling pathways mediated by cGMP-dependent protein kinase. By selectively blocking PKG activity, Rp-8-Br-cGMPS allows scientists to dissect the role of cGMP and PKG in processes such as vasodilation, platelet aggregation, and neuronal signaling. It is also valuable in exploring the mechanisms of learning and memory, as PKG is implicated in long-term potentiation within the hippocampus. Additionally, research involving Rp-8-Br-cGMPS contributes to the understanding of smooth muscle relaxation and cardiovascular function. The compound′s specificity in inhibiting PKG-related pathways is critical for elucidating the physiological and pathological roles of cGMP signaling.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rp-8-Br-cGMPS, 500 µg | sc-200323 | 500 µg | $270.00 |