Ristocetin Sulfate Salt (CAS 1404-55-3)
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Ristocetin sulfate salt is a glycopeptide compound that is integral to research in the field of hematology, particularly in studying platelet function and blood coagulation mechanisms. It is used to induce platelet agglutination in vitro, which is essential for the assessment of von Willebrand factor (vWF) activity and the diagnosis of von Willebrand disease. Researchers utilize ristocetin sulfate salt to better understand the interaction between vWF and platelet glycoprotein Ib-IX-V complex. In addition, it serves as a tool in the investigation of platelet adhesion under various flow conditions, contributing to the broader knowledge of thrombosis and hemostasis. Moreover, ristocetin sulfate salt is used in biochemical assays to explore the binding characteristics and function of vWF in the blood coagulation pathway.
Ristocetin Sulfate Salt (CAS 1404-55-3) References
- Enantioselective supercritical fluid chromatography using ristocetin A chiral stationary phases. | Svensson, LA. and Owens, PK. 2000. Analyst. 125: 1037-9. PMID: 10932849
- Interaction of purified type IIB von Willebrand factor with the platelet membrane glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and initiates aggregation. | De Marco, L., et al. 1985. Proc Natl Acad Sci U S A. 82: 7424-8. PMID: 2932740
- Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregation. | De Marco, L., et al. 1985. J Clin Invest. 75: 1198-203. PMID: 3157702
- Artificial cerebrospinal fluid restores aspirin-inhibited physiological hemostasis through recovery of platelet aggregation function. | Suzuki, R., et al. 2023. Acta Neurochir (Wien). 165: 1269-1276. PMID: 36595058
- Highly enantioselective capillary electrophoretic separations with dilute solutions of the macrocyclic antibiotic ristocetin A. | Armstrong, DW., et al. 1995. J Chromatogr A. 689: 285-304. PMID: 7874302
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ristocetin Sulfate Salt, 5 mg | sc-296272 | 5 mg | $117.00 | |||
Ristocetin Sulfate Salt, 25 mg | sc-296272A | 25 mg | $520.00 |