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Retinyl acetate (CAS 127-47-9)

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Alternate Names:
Vitamin A acetate
Application:
Retinyl acetate is an antiproliferative analog of vitamin A
CAS Number:
127-47-9
Molecular Weight:
328.49
Molecular Formula:
C22H32O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Retinyl acetate, a variant of vitamin A, holds multifaceted applications in the realms of medicine, science, and industry. Its characteristics include being a colorless, slightly viscous liquid with solubility in most organic solvents. Naturally occurring, retinyl acetate serves as a precursor to the biologically active form of vitamin A known as retinoic acid. Its primary uses revolve around dietary supplementation and its longstanding presence in the cosmetics industry. The precise mechanism of action behind retinyl acetate remains incompletely understood. However, it is believed to scavenge free radicals. Furthermore, it is thought to exert influence over gene expression and affect the activity of specific enzymes and proteins.


Retinyl acetate (CAS 127-47-9) References

  1. Effect of retinyl acetate on sulfated glycosaminoglycan biosynthesis in dermal and epidermal cells in vitro.  |  Shapiro, SS. and Poon, JP. 1978. Connect Tissue Res. 6: 101-8. PMID: 152687
  2. Effects of retinyl acetate on surface morphology and intramembrane particle distribution in the plasma membrane of 10T1/2 cells.  |  Fassel, TA., et al. 1991. J Struct Biol. 107: 97-105. PMID: 1807353
  3. Retinyl acetate-loaded nanoparticles: dermal penetration and release of the retinyl acetate.  |  Arayachukeat, S., et al. 2011. Int J Pharm. 404: 281-8. PMID: 21093565
  4. Effect of retinyl acetate and 4-hydroxyphenylretinamide on initiation of chemically-induced mammary tumors.  |  Grubbs, CJ., et al. 1990. Anticancer Res. 10: 661-6. PMID: 2142393
  5. Quantification of β-carotene, retinol, retinyl acetate and retinyl palmitate in enriched fruit juices using dispersive liquid-liquid microextraction coupled to liquid chromatography with fluorescence detection and atmospheric pressure chemical ionization-mass spectrometry.  |  Viñas, P., et al. 2013. J Chromatogr A. 1275: 1-8. PMID: 23290361
  6. Controlled release of retinyl acetate from β-cyclodextrin functionalized poly(vinyl alcohol) electrospun nanofibers.  |  Lemma, SM., et al. 2015. J Agric Food Chem. 63: 3481-8. PMID: 25779354
  7. A new model of detrusor overactivity in conscious rats induced by retinyl acetate instillation.  |  Wróbel, A., et al. 2015. J Pharmacol Toxicol Methods. 74: 7-16. PMID: 25957030
  8. Effect of retinyl acetate on transglutaminase 2 activity in carcinogen treated rat liver.  |  Aydin, O., et al. 2016. Biotech Histochem. 91: 342-51. PMID: 27089473
  9. Retinyl acetate inhibits estrogen-induced mammary carcinogenesis in female ACI rats.  |  Holtzman, S. 1988. Carcinogenesis. 9: 305-7. PMID: 3123084
  10. The influence of Potentilla chinensis aqueous extract on urinary bladder function in retinyl acetate-induced detrusor overactivity in rats.  |  Wróbel, A., et al. 2020. Biomed Pharmacother. 132: 110861. PMID: 33113423
  11. Retinyl acetate effects on the life span and the incidence of cryptogenic neoplasms in C3H mice.  |  Stenbäck, F., et al. 1987. Nutr Cancer. 10: 119-28. PMID: 3628036
  12. Modulation by retinyl acetate of microfilament bundle formation in C3H/10T1/2 cells.  |  Mordan, LJ., et al. 1984. J Cell Biochem. 24: 15-25. PMID: 6539338
  13. Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea.  |  Moon, RC., et al. 1977. Nature. 267: 620-1. PMID: 876383

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Retinyl acetate, 10 g

sc-204878
10 g
$316.00

Retinyl acetate, 25 g

sc-204878A
25 g
$520.00