Molecular structure of Retinamide, CAS Number: 20638-84-0
Retinamide (CAS 20638-84-0)
Alternate Names:
Ro 4-3930; all-trans-Vitamin A Amide
Application:
Retinamide is a selective and potent apoptosis-inducing agent derived from Vitamin A
CAS Number:
20638-84-0
Molecular Weight:
299.45
Molecular Formula:
C20H29NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Retinamide is a selective and potent apoptosis-inducing agent derived from Vitamin A. It works by binding to nuclear receptors and triggering a cascade of biochemical reactions that lead to changes in gene expression and the formation of new proteins. This ultimately leads to changes in cellular function and behavior. Retinamide has been found to stimulate cell proliferation, induce cell differentiation, and inhibit cell death. It has also been shown to modulate the expression of genes involved in cell cycle regulation, apoptosis, and inflammation. Furthermore, Retinamide has been used to study the effects of Vitamin A on cell differentiation and development, as well as its role in cancer research.
Retinamide (CAS 20638-84-0) References
- Retinoids and cancer prevention. | Hill, DL. and Grubbs, CJ. 1992. Annu Rev Nutr. 12: 161-81. PMID: 1503802
- Retinamide-induced apoptosis in glioblastomas is associated with down-regulation of Bcl-xL and Bcl-2 proteins. | Lytle, RA., et al. 2005. J Neurooncol. 74: 225-32. PMID: 16187019
- Chemoprevention in gastrointestinal cancers: current status. | Grau, MV., et al. 2006. Basic Clin Pharmacol Toxicol. 98: 281-7. PMID: 16611203
- [Effects of N-(P-carboxylpheyl)-retinamide on ECa109-C3 cells in vitro--observation with transmission electron microscopy]. | Ning, AA. 1986. Zhonghua Zhong Liu Za Zhi. 8: 11-3. PMID: 3732018
- Subacute toxicity of all-trans- and 13-cis-isomers of N-ethyl retinamide, N-2-hydroxyethyl retinamide, and N-4-hydroxyphenyl retinamide. | Sani, BP. and Meeks, RG. 1983. Toxicol Appl Pharmacol. 70: 228-35. PMID: 6226123
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Retinamide, 1 mg | sc-212773 | 1 mg | $313.00 |