(R)-mono-Ethyl 3-acetoxyglutarate (CAS 113036-11-6)

(R)-mono-Ethyl 3-acetoxyglutarate is an important chiral intermediate extensively used in organic synthesis and biochemical research. This compound plays a significant role in the study of enzyme-catalyzed reactions and stereoselective synthesis processes. Its structure, featuring an ester and an acetoxy group, makes it a valuable building block for the synthesis of complex molecules, particularly in the development of chiral pharmaceuticals and natural product derivatives. Researchers utilize (R)-mono-Ethyl 3-acetoxyglutarate to explore mechanisms of asymmetric catalysis, focusing on how enzymes and synthetic catalysts differentiate between enantiomers to produce chiral molecules with high selectivity. In biochemistry, this compound serves as a substrate for enzymes involved in the tricarboxylic acid (TCA) cycle, aiding in the study of metabolic pathways and the role of chiral intermediates in cellular metabolism. Additionally, (R)-mono-Ethyl 3-acetoxyglutarate is used in the synthesis of optically active compounds through esterification and hydrolysis reactions, providing insights into reaction mechanisms and the development of new synthetic methodologies. Its application extends to the study of enzyme kinetics, where it helps explain the binding and transformation of chiral substrates by specific enzymes. Overall, (R)-mono-Ethyl 3-acetoxyglutarate is a crucial reagent in advancing our understanding of stereochemistry, enzyme function, and organic synthesis techniques.