Date published: 2025-10-9

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(R)-(+)-Mandelonitrile (CAS 10020-96-9)

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Application:
(R)-(+)-Mandelonitrile is an intermediary obtained during the preparation of optically active α-hydroxy carboxylic acids
CAS Number:
10020-96-9
Purity:
≥97%
Molecular Weight:
133.15
Molecular Formula:
C8H7NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(R)-(+)-Mandelonitrile is an enantiomerically pure compound often utilized in the field of organic chemistry and catalysis research. It is investigated for its role as a precursor in the synthesis of chiral intermediates. The compound′s nitrile group can be transformed through various chemical reactions, which makes (R)-(+)-Mandelonitrile a versatile starting material for producing a wide range of enantiomerically enriched products. Researchers also study the compound in the context of enzyme-catalyzed transformations, where it can serve as a substrate for nitrilases and nitrile hydratases, enzymes that are of interest for their potential in the production of optically pure carboxylic acids and amides. In addition, (R)-(+)-Mandelonitrile is used in mechanistic studies to understand the principles of asymmetric synthesis and stereoselectivity, which are fundamental concepts in the development of new chiral materials.


(R)-(+)-Mandelonitrile (CAS 10020-96-9) References

  1. Molecular analysis of (R)-(+)-mandelonitrile lyase microheterogeneity in black cherry.  |  Hu, Z. and Poulton, JE. 1999. Plant Physiol. 119: 1535-46. PMID: 10198113
  2. Immunocytochemical Localization of Prunasin Hydrolase and Mandelonitrile Lyase in Stems and Leaves of Prunus serotina.  |  Swain, E. and Poulton, JE. 1994. Plant Physiol. 106: 1285-1291. PMID: 12232409
  3. Immunocytochemical Localization of Mandelonitrile Lyase in Mature Black Cherry (Prunus serotina Ehrh.) Seeds.  |  Wu, HC. and Poulton, JE. 1991. Plant Physiol. 96: 1329-37. PMID: 16668338
  4. Temporal and spatial expression of amygdalin hydrolase and (R)-(+)-mandelonitrile lyase in black cherry seeds.  |  Zheng, L. and Poulton, JE. 1995. Plant Physiol. 109: 31-9. PMID: 7480328
  5. Crystallization and preliminary X-ray diffraction studies of mandelonitrile lyase from almonds.  |  Lauble, H., et al. 1994. Proteins. 19: 343-7. PMID: 7984630
  6. Sequencing, genomic organization, and preliminary promoter analysis of a black cherry (R)-(+)-mandelonitrile lyase gene.  |  Hu, Z. and Poulton, JE. 1997. Plant Physiol. 115: 1359-69. PMID: 9414550
  7. Molecular cloning of the cDNA coding for the (R)-(+)-mandelonitrile lyase of Prunus amygdalus: temporal and spatial expression patterns in flowers and mature seeds.  |  Suelves, M. and Puigdomènech, P. 1998. Planta. 206: 388-93. PMID: 9763708

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(R)-(+)-Mandelonitrile, 1 g

sc-250880
1 g
$55.00

(R)-(+)-Mandelonitrile, 10 g

sc-250880A
10 g
$250.00

(R)-(+)-Mandelonitrile, 25 g

sc-250880B
25 g
$362.00

(R)-(+)-Mandelonitrile, 50 g

sc-250880C
50 g
$617.00

(R)-(+)-Mandelonitrile, 100 g

sc-250880D
100 g
$821.00