Quillaic Acid (CAS 631-01-6)
CAS Number:
631-01-6
Molecular Weight:
486.68
Molecular Formula:
C30H46O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Quillaic acid functions as a surfactant, aiding in the emulsification of non-polar substances in aqueous solutions. It achieves this by reducing the surface tension between the non-polar and polar phases, allowing for the formation of stable emulsions. At the molecular level, quillaic acid interacts with the interface between the non-polar and polar phases, facilitating the dispersion of non-polar substances such as oils or fats in water-based solutions. This mechanism of action enables the creation of stable emulsions, which is particularly useful in various experimental applications where the dispersion of non-polar substances in aqueous solutions is required.
Quillaic Acid (CAS 631-01-6) References
- Analysis of bisdesmosidic saponins in Saponaria vaccaria L. by HPLC-PAD-MS: identification of new quillaic acid and gypsogenin 3-O-trisaccharides. | Balsevich, JJ., et al. 2006. Phytochem Anal. 17: 414-23. PMID: 17144250
- Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. | Arrau, S., et al. 2011. J Ethnopharmacol. 133: 164-7. PMID: 20951193
- Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. | Rodríguez-Díaz, M., et al. 2011. J Pharm Pharmacol. 63: 718-24. PMID: 21492174
- Nebulosides A-B, novel triterpene saponins from under-ground parts of Gypsophila arrostii Guss. var. nebulosa. | Arslan, I., et al. 2013. Bioorg Med Chem. 21: 1279-83. PMID: 23352756
- Antiproliferative quillaic acid and gypsogenin saponins from Saponaria officinalis L. roots. | Lu, Y., et al. 2015. Phytochemistry. 113: 108-20. PMID: 25534953
- Two new triterpenoids from Gypsophila oldhamiana. | Xie, LX., et al. 2016. Nat Prod Res. 30: 1068-74. PMID: 26539898
- Quillaja Saponin Characteristics and Functional Properties. | Reichert, CL., et al. 2019. Annu Rev Food Sci Technol. 10: 43-73. PMID: 30664381
- Synthesis and Evaluation of QS-7-Based Vaccine Adjuvants. | Wang, P., et al. 2019. ACS Infect Dis. 5: 974-981. PMID: 30920199
- Antihyperalgesic Activity of Quillaic Acid Obtained from Quillaja Saponaria Mol. | Arrau, S., et al. 2019. Curr Top Med Chem. 19: 927-930. PMID: 31072292
- Impact of C28 Oligosaccharide on Adjuvant Activity of QS-7 Analogues. | Škalamera, Đ., et al. 2020. J Org Chem. 85: 15837-15848. PMID: 32463234
- In vitro evaluation and molecular docking of QS-21 and quillaic acid from Quillaja saponaria Molina as gastric cancer agents. | Guzmán, L., et al. 2020. Sci Rep. 10: 10534. PMID: 32601436
- Highlighting Aglycone-dependent Glycosylation Aspects in Caryophyllaceae Saponins by a Simplex Simulation Approach. | Hammami, A., et al. 2021. Curr Top Med Chem. 21: 612-627. PMID: 33459236
- De Novo Biosynthesis of the Oleanane-Type Triterpenoids of Tunicosaponins in Yeast. | Li, W., et al. 2021. ACS Synth Biol. 10: 1874-1881. PMID: 34259519
- Synthesis and evaluation of anticancer activity of quillaic acid derivatives: A cell cycle arrest and apoptosis inducer through NF-κB and MAPK pathways. | Huang, X., et al. 2022. Front Chem. 10: 951713. PMID: 36157038
- Modulators of diabetic neuropathy and inflammation from Saponaria officinalis: Isolation of active phytochemicals and potential mechanisms of action. | Raafat, K. and Al Haj, M. 2023. J Tradit Complement Med. 13: 226-235. PMID: 37128196
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Quillaic Acid, 10 mg | sc-476331 | 10 mg | $388.00 |