Date published: 2025-10-20

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Polypropylene glycol (CAS 25322-69-4)

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Alternate Names:
PPG; Poly(propylene oxide)
CAS Number:
25322-69-4
Molecular Weight:
~425
Molecular Formula:
H[OC3H6]nOH
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Polypropylene glycol is a compound that functions as a surfactant and emulsifier in experimental applications. It acts by reducing the surface tension between two substances, allowing them to mix more effectively. Polypropylene glycol′s mode of action involves interacting with the interfaces between different phases, such as oil and water, to stabilize the mixture. At the molecular level, polypropylene glycol forms a protective barrier around droplets of one substance in another. Polypropylene glycol′s function is to facilitate the dispersion of one substance within another, promoting homogeneity and stability in experimental formulations. Its mode of action involves altering the interfacial properties of the substances involved, enabling them to remain uniformly distributed.


Polypropylene glycol (CAS 25322-69-4) References

  1. Polypropylene glycol phosphate methacrylate as an alternative acid-functional monomer on self-etching adhesives.  |  Münchow, EA., et al. 2015. J Dent. 43: 94-102. PMID: 25449956
  2. Adenine-functionalized polypropylene glycol: A novel stationary phase for gas chromatography offering good inertness for acids and bases combined with a unique selectivity.  |  Xiong, X. and Qi, M. 2020. J Chromatogr A. 1612: 460627. PMID: 31668867
  3. Aqueous polypropylene glycol induces swelling and severe plasticization of high Tg amphiphilic copolymers containing hexafluoroisopropanol groups.  |  Li, S. and Vogt, BD. 2020. Soft Matter. 16: 6362-6370. PMID: 32568344
  4. Chitosan/polypropylene glycol hydrogel composite film designed with TiO2 nanoparticles: A promising scaffold of biomedical applications.  |  Ulu, A., et al. 2020. Int J Biol Macromol. 163: 529-540. PMID: 32640322
  5. Effects of Polypropylene Glycol at Very Low Concentrations on Rheological Properties at the Air-Water Interface and Foam Stability of Sodium Bis(2-ethylhexyl)sulfosuccinate Aqueous Solutions.  |  Aono, K., et al. 2020. Langmuir. 36: 10043-10050. PMID: 32787049
  6. Development of an ethanolic two-phase system (ETPS) based on polypropylene glycol 2000 + ethylene glycol + ethanol for separation of hydrophobic compounds.  |  Buarque, FS., et al. 2021. Chem Commun (Camb). 57: 2156-2159. PMID: 33523051
  7. Cashew Gum Polysaccharide Nanoparticles Grafted with Polypropylene Glycol as Carriers for Diclofenac Sodium.  |  Silva, CNSD., et al. 2021. Materials (Basel). 14: PMID: 33922015
  8. Colorimetric sensing of cephradine through polypropylene glycol functionalized gold nanoparticles.  |  Raja, DA., et al. 2021. R Soc Open Sci. 8: 210185. PMID: 34084550
  9. Optimization of Bioactive Phenolics Extraction and Cosmeceutical Activity of Eco-Friendly Polypropylene-Glycol-Lactic-Acid-Based Extracts of Olive Leaf.  |  Marijan, M., et al. 2022. Molecules. 27: PMID: 35056847
  10. Influence of RAFT Agent on the Mechanism of Copolymerization of Polypropylene Glycol Maleinate with Acrylic Acid.  |  Burkeev, MZ., et al. 2022. Polymers (Basel). 14: PMID: 35567053
  11. Quantitative analysis of polypropylene glycol polymers by liquid chromatography tandem mass spectrometry based on collision induced dissociation technique.  |  Shi, M., et al. 2022. J Chromatogr A. 1676: 463214. PMID: 35709604
  12. In Situ Observation of Shear-Induced Jamming Front Propagation during Low-Velocity Impact in Polypropylene Glycol/Fumed Silica Shear Thickening Fluids.  |  Kurkin, A., et al. 2022. Polymers (Basel). 14: PMID: 35890543
  13. Precise Non-Equilibrium Polypropylene Glycol Polyrotaxanes.  |  Seale, JSW., et al. 2022. J Am Chem Soc. 144: 16898-16904. PMID: 36074552

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Polypropylene glycol, 5 g

sc-255443
5 g
$295.00