Molecular structure of (+)-Norfenfluramine hydrochloride, CAS Number: 37936-89-3
(+)-Norfenfluramine hydrochloride (CAS 37936-89-3)
Application:
(+)-Norfenfluramine hydrochloride is a major hepatic metabolite of (+)-fenfluramine
CAS Number:
37936-89-3
Purity:
≥98%
Molecular Weight:
239.67
Molecular Formula:
C10H12F3N•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; more potent than fenfluramine at inducing dopamine release; acts primarily on the cytoplasmic pool of serotonin.
(+)-Norfenfluramine hydrochloride (CAS 37936-89-3) References
Ni, W., et al.,, The 5-HT2A receptor is involved in (+)-norfenfluramine-induced arterial contraction and blood pressure increase in DOCA-salt hypertension. J. Pharmacol. Exp. Ther., (2007) Gobbi, M., et al.,, In vitro studies on the mechanism by which (+)-norfenfluramine induces serotonin and dopamine release from the vesicular storage pool. Naunyn Schmiedebergs Arch. Pharmacol. 358, 323-327, (1998)Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Norfenfluramine hydrochloride, 10 mg | sc-253200 | 10 mg | $142.00 | |||
(+)-Norfenfluramine hydrochloride, 50 mg | sc-253200A | 50 mg | $640.00 |