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5-iPF2α-VI-d11 contains 11 deuterium atoms and is intended for use as an internal standard for quantification of 5-iPF2α-VI (sc-205138) by GC- or LC-mass spectrometry. Isoprostanes are prostaglandin-like products of free-radical induced lipid peroxidation. iPF2α-VI is one of dozens of possible stereo- and regioisomeric isoprostanes that can be formed from arachidonic acid. As of now, the most extensively studied of these is 8-isoprostane (8-epi-PGF2α, iPF2α-III) (sc-201261). However, 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers that form in natural conditions of oxidative stress, including iPF2α-VI of the type-VI isoprostanes. This class has been shown to be one of the major isoprostane products, in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane, Type VI isoprostanes form internal lactones which facilitate their extraction and purification from biological samples.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)5-iPF2α-VI-d11, 10 µg | sc-221031 | 10 µg | $600.00 | |||
(±)5-iPF2α-VI-d11, 25 µg | sc-221031A | 25 µg | $1405.00 |