Date published: 2026-2-8

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(±)19,20-DiHDPA

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Application:
(±)19,20-DiHDPA is a major metabolite produced when DHA is incubated with NADPH-supplemented rat liver microsomes.
Molecular Weight:
362.5
Molecular Formula:
C22H34O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)19,20-DiHDPA, identified by its CAS registry number, is a hydroxylated derivative of docosapentaenoic acid (DPA), an omega-3 fatty acid, which has been pivotal in research focusing on lipid biochemistry and cellular physiology. This compound features hydroxyl groups at the 19th and 20th carbon positions, enhancing its polarity and potentially affecting its interaction with other biomolecules. Within research contexts, (±)19,20-DiHDPA has been extensively studied for its role in modulating lipid signaling pathways and influencing the biophysical properties of cellular membranes. The presence of hydroxyl groups is believed to affect the compound′s interaction with lipid membranes, possibly altering their curvature and packing characteristics, which are crucial for the formation and stability of lipid rafts and signaling platforms. Furthermore, this chemical′s configuration allows it to participate in the biosynthesis of specialized pro-resolving mediators (SPMs), which are critical in the resolution phase of inflammatory responses. Researchers have utilized (±)19,20-DiHDPA in experimental setups to delve into the mechanisms by which omega-3 derivatives influence cell signaling, potentially impacting a range of cellular functions from membrane dynamics to intracellular signaling cascades. This research has provided a deeper understanding of lipid-mediated cell signaling and its role in cellular homeostasis and response mechanisms.


(±)19,20-DiHDPA References

  1. Non-Targeted LC-MS/MS Assay for Screening Over 100 Lipid Mediators from ARA, EPA, and DHA in Biological Samples Based on Mass Spectral Fragmentations.  |  Dasilva, G., et al. 2019. Molecules. 24: PMID: 31248084

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)19,20-DiHDPA, 50 µg

sc-220657
50 µg
$139.00

(±)19,20-DiHDPA, 100 µg

sc-220657A
100 µg
$265.00