Date published: 2026-5-26

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(±)-1,2,4-Butanetriol (CAS 3068-00-6)

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CAS Number:
3068-00-6
Purity:
≥98%
Molecular Weight:
106.12
Molecular Formula:
C4H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)-1,2,4-Butanetriol is a chiral compound with application in chemical synthesis research for its applicability as a multifunctional building block. Its array of hydroxyl groups makes it an ideal candidate for the study of polyol reactions and the synthesis of complex polyesters and polyurethanes, which are of interest in the development of new materials. In the field of green chemistry, (±)-1,2,4-Butanetriol is investigated for its potential as a starting material in the production of biodegradable polymers, contributing to the creation of more environmentally friendly products. Additionally, its stereochemistry is pertinent to research in stereoselective synthesis, offering a platform for the exploration of asymmetric catalytic processes. The compound also plays a role in energy research, where it is explored as a precursor for the generation of high-energy chemical compounds that can be used as fuel additives.


(±)-1,2,4-Butanetriol (CAS 3068-00-6) References

  1. Microbial synthesis of the energetic material precursor 1,2,4-butanetriol.  |  Niu, W., et al. 2003. J Am Chem Soc. 125: 12998-9. PMID: 14570452
  2. Production of optically active 1,2,4-butanetriol from corresponding racemate by Microbial stereoinversion.  |  Yamada-Onodera, K., et al. 2007. J Biosci Bioeng. 103: 494-6. PMID: 17609168
  3. GroESL overexpression imparts Escherichia coli tolerance to i-, n-, and 2-butanol, 1,2,4-butanetriol and ethanol with complex and unpredictable patterns.  |  Zingaro, KA. and Terry Papoutsakis, E. 2013. Metab Eng. 15: 196-205. PMID: 22898718
  4. Design and construction of a non-natural malate to 1,2,4-butanetriol pathway creates possibility to produce 1,2,4-butanetriol from glucose.  |  Li, X., et al. 2014. Sci Rep. 4: 5541. PMID: 25008973
  5. Synthetic pathway optimization for improved 1,2,4-butanetriol production.  |  Sun, L., et al. 2016. J Ind Microbiol Biotechnol. 43: 67-78. PMID: 26498325
  6. Biotechnological production of 1,2,4-butanetriol: An efficient process to synthesize energetic material precursor from renewable biomass.  |  Cao, Y., et al. 2015. Sci Rep. 5: 18149. PMID: 26670289
  7. Improved 1, 2, 4-butanetriol production from an engineered Escherichia coli by co-expression of different chaperone proteins.  |  Lu, X., et al. 2016. World J Microbiol Biotechnol. 32: 149. PMID: 27430516
  8. Metabolic pathway optimization for biosynthesis of 1,2,4-butanetriol from xylose by engineered Escherichia coli.  |  Zhang, N., et al. 2016. Enzyme Microb Technol. 93-94: 51-58. PMID: 27702485
  9. Theoretical studies of the decomposition mechanisms of 1,2,4-butanetriol trinitrate.  |  Pei, L., et al. 2017. J Mol Model. 24: 6. PMID: 29214359
  10. Modification of an engineered Escherichia coli by a combined strategy of deleting branch pathway, fine-tuning xylose isomerase expression, and substituting decarboxylase to improve 1,2,4-butanetriol production.  |  Jing, P., et al. 2018. J Biosci Bioeng. 126: 547-552. PMID: 29945765
  11. Production of 1,2,4-butanetriol from xylose by Saccharomyces cerevisiae through Fe metabolic engineering.  |  Bamba, T., et al. 2019. Metab Eng. 56: 17-27. PMID: 31434008
  12. Discovering a novel D-xylonate-responsive promoter: the PyjhI-driven genetic switch towards better 1,2,4-butanetriol production.  |  Bañares, AB., et al. 2019. Appl Microbiol Biotechnol. 103: 8063-8074. PMID: 31482281
  13. Coupled biosynthesis and esterification of 1,2,4-butanetriol to simplify its separation from fermentation broth.  |  Feng, X., et al. 2019. Eng Life Sci. 19: 444-451. PMID: 32625021

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-1,2,4-Butanetriol, 25 ml

sc-237700
25 ml
$117.00