Molecular structure of PLURONIC® F-127, sterile-filtered, CAS Number: 9003-11-6
PLURONIC® F-127, sterile-filtered (CAS 9003-11-6)
Alternate Names:
Poloxamer 407; Polyoxypropylenepolyoxyethylene Block Copolymer
Application:
PLURONIC® F-127, sterile-filtered is a non-ionic detergent useful for isolation of membrane proteins
CAS Number:
9003-11-6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PLURONIC® F-127, sterile-filtered, is a non-ionic detergent useful for isolation of membrane proteins. PLURONIC® F-127, sterile-filtered has been used to solubilize large dye molecules in physiological media. Because of its low UV absorbance, PLURONIC® F-127, sterile-filtered can be used in protocols that require UV monitoring of the solubilized proteins.
PLURONIC,[object Object], F-127, sterile-filtered (CAS 9003-11-6) References
- Enzymatic degradation of SLN-effect of surfactant and surfactant mixtures. | Olbrich, C. and Müller, RH. 1999. Int J Pharm. 180: 31-9. PMID: 10089289
- Detection and determination of surface levels of poloxamer and PVA surfactant on biodegradable nanospheres using SSIMS and XPS. | Scholes, PD., et al. 1999. J Control Release. 59: 261-78. PMID: 10332059
- Effects of non-ionic surfactants as permeation enhancers towards piroxicam from the poloxamer gel through rat skins. | Shin, SC., et al. 2001. Int J Pharm. 222: 199-203. PMID: 11427350
- Influence of surface-modifying surfactants on the pharmacokinetic behavior of 14C-poly (methylmethacrylate) nanoparticles in experimental tumor models. | Lode, J., et al. 2001. Pharm Res. 18: 1613-9. PMID: 11758771
- Temporary vascular occlusion with poloxamer 407. | Raymond, J., et al. 2004. Biomaterials. 25: 3983-9. PMID: 15046888
- Influence of the surface properties of low contact angle surfactants on the body distribution of 14C-poly(methyl methacrylate) nanoparticles. | Tröster, SD. and Kreuter, J. 1992. J Microencapsul. 9: 19-28. PMID: 1613640
- Hyperlipidemia and surfactants: the liver sieve is a link. | Cogger, VC., et al. 2006. Atherosclerosis. 189: 273-81. PMID: 16458315
- The effect of surfactants on the dissolution behavior of amorphous formulations. | Mah, PT., et al. 2016. Eur J Pharm Biopharm. 103: 13-22. PMID: 26955750
- Thermogelling properties of purified poloxamer 407. | Fakhari, A., et al. 2017. Heliyon. 3: e00390. PMID: 28920092
- Poloxamer 407/TPGS Mixed Micelles as Promising Carriers for Cyclosporine Ocular Delivery. | Grimaudo, MA., et al. 2018. Mol Pharm. 15: 571-584. PMID: 29313693
- Poloxamer 407 based-nanoparticles for controlled release of methotrexate. | Moura, S., et al. 2020. Int J Pharm. 575: 118924. PMID: 31870962
- Third-generation solid dispersion combining Soluplus and poloxamer 407 enhances the oral bioavailability of resveratrol. | Vasconcelos, T., et al. 2021. Int J Pharm. 595: 120245. PMID: 33484925
- Role of Surfactant Micellization for Enhanced Dissolution of Poorly Water-Soluble Cilostazol Using Poloxamer 407-Based Solid Dispersion via the Anti-Solvent Method. | Jin, G., et al. 2021. Pharmaceutics. 13: PMID: 34063136
- Poloxamer 407 Induces Hypertriglyceridemia but Decreases Atherosclerosis in Ldlr-/- Mice. | Peng, X., et al. 2022. Cells. 11: PMID: 35681489
- Mechanism of poloxamer 407-induced hypertriglyceridemia in the rat. | Johnston, TP. and Palmer, WK. 1993. Biochem Pharmacol. 46: 1037-42. PMID: 8216346
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PLTP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PLURONIC® F-127, sterile-filtered, 50 ml | sc-281131 | 50 ml | $332.00 |