Pitavastatin Lactone is a major phase 2 metabolite of pitavastatin, an inhibitor of HMG-CoA reductase. Studies have shown that conversion between the acid and lactone forms of pitavastatin occurs in the body and that these two forms differ in substrate activity tow.
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See how others have used Pitavastatin Lactone (CAS 141750-63-2). Click on the entry to view the PubMed entry .
PMID: # 33341662 Shiozawa, A.|Yamaori, S.|Kamijo, S.|Ohmori, S.| et al. 2020. Drug Metab Pharmacokinet. 36: 100364.
PMID: # 25318994 Hosaka, S. et al. 2015. Drug Metab. Dispos. 43: 27-33.
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