Molecular structure of Pipemidic acid, CAS Number: 51940-44-4
Pipemidic acid (CAS 51940-44-4)
Alternate Names:
8-Ethyl-5,8-dihydro-5-oxo-2-(1-piperazinyl)pyrido(2,3-d)pyrimidine-6-carboxylic acid
Application:
Pipemidic acid is an antibiotic and cell selection agent
CAS Number:
51940-44-4
Molecular Weight:
303.32
Molecular Formula:
C14H17N5O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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In the area of analytical and environmental chemistry, pipemidic acid is a compound of interest for its role as a chemical marker in the development of detection methods, such as high-performance liquid chromatography and mass spectrometry. Researchers rely on it for its consistent spectral properties which are invaluable for instrument calibration and method validation. Moreover, its behavior in environmental systems is studied to understand the fate of similar organic molecules, particularly their transport, biodegradation, and potential bioaccumulation. Additionally, pipemidic acid′s structure is utilized in synthetic chemistry research to explore new pathways for the creation of complex molecules, enhancing the repertoire of synthetic methodologies.
Pipemidic acid (CAS 51940-44-4) References
- Pipemidic acid: absorption, distribution, and excretion. | Shimizu, M., et al. 1975. Antimicrob Agents Chemother. 7: 441-6. PMID: 1147580
- Pipemidic acid: its activities against various experimental infections. | Shimizu, M., et al. 1976. Antimicrob Agents Chemother. 9: 569-74. PMID: 1267435
- Determination of pipemidic acid based on flow-injection chemiluminescence due to energy transfer from peroxynitrous acid synthesized on-line. | Liang, YD., et al. 2004. Anal Bioanal Chem. 380: 918-23. PMID: 15568139
- Simultaneous determination of proline and pipemidic acid in human urine by capillary electrophoresis with electrochemiluminescence detection. | Sun, H., et al. 2010. J Clin Lab Anal. 24: 327-33. PMID: 20872568
- β-Cyclodextrin inclusion complex to improve physicochemical properties of pipemidic acid: characterization and bioactivity evaluation. | Iacovino, R., et al. 2013. Int J Mol Sci. 14: 13022-41. PMID: 23799358
- Effect of nalidixic acid, pipemidic acid and cinoxacin on chondrocyte metabolism in explants of articular cartilage. | Brand, HS., et al. 1990. Clin Exp Rheumatol. 8: 393-5. PMID: 2397627
- Synthesis and in vitro antimicrobial activity screening of new pipemidic acid derivatives. | Popiołek, Ł., et al. 2018. Arch Pharm Res. 41: 633-645. PMID: 29619676
- Nanoparticles with high payloads of pipemidic acid, a poorly soluble crystalline drug: drug-initiated polymerization and self-assembly approach. | Pancani, E., et al. 2018. Acta Pharm Sin B. 8: 420-431. PMID: 29881681
- A New Approach for Improving the Antibacterial and Tumor Cytotoxic Activities of Pipemidic Acid by Including It in Trimethyl-β-cyclodextrin. | Lavorgna, M., et al. 2019. Int J Mol Sci. 20: PMID: 30669399
- Bioactivity of Isostructural Hydrogen Bonding Frameworks Built from Pipemidic Acid Metal Complexes. | Alves, PC., et al. 2020. Molecules. 25: PMID: 32443884
- Water Flow and Dissolved MnII Alter Transformation of Pipemidic Acid by Manganese Oxide. | Pokharel, R., et al. 2020. Environ Sci Technol. 54: 8051-8060. PMID: 32470299
- Pipemidic acid, a new treatment for recurrent urinary tract infection in small animals. | van Oosterom, RA. and Hartman, EG. 1986. Vet Q. 8: 2-5. PMID: 3515744
- Determination of pipemidic acid in plasma by normal-phase high-pressure liquid chromatography. | Ito, H., et al. 1985. Antimicrob Agents Chemother. 28: 192-4. PMID: 3834829
- Comparative activities of ciprofloxacin (Bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid. | Muytjens, HL., et al. 1983. Antimicrob Agents Chemother. 24: 302-4. PMID: 6227281
- Metabolites of pipemidic acid in human urine. | Kurobe, N., et al. 1980. Xenobiotica. 10: 37-46. PMID: 7385914
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pipemidic acid, 10 g | sc-236402 | 10 g | $151.00 |