Phosphazene base P1-t-Bu-tris(tetramethylene) (CAS 161118-67-8)

Phosphazene base P1-t-Bu-tris(tetramethylene), referred to as BTTP, is an innovative synthetic compound with anti-inflammatory, anti-tumor, and antiviral activities in vitro. Furthermore, it has garnered attention for its capacity to modulate enzymes involved in energy metabolism, particularly by inhibiting adenosine monophosphate-activated protein kinase (AMPK). Phosphazene base P1-t-Bu-tris(tetramethylene) has undergone extensive examination within various scientific research domains. Investigations have explored its ability to regulate enzymes involved in energy metabolism, such as the inhibitory effects on AMPK. The precise mechanism of action underlying Phosphazene base P1-t-Bu-tris(tetramethylene)′s effects remains under investigation however, current understanding suggests its binding to AMPK′s active site, resulting in inhibition. Moreover, Phosphazene base P1-t-Bu-tris(tetramethylene) has demonstrated inhibitory effects on other energy metabolism enzymes, including phosphofructokinase and acetyl-CoA carboxylase.