Molecular structure of Phosphamidon, CAS Number: 13171-21-6
Phosphamidon (CAS 13171-21-6)
Alternate Names:
2-Chloro-N,N-diethyl-3-(dimethylphosphono)crotonic amide
CAS Number:
13171-21-6
Purity:
≥90%
Molecular Weight:
299.69
Molecular Formula:
C10H19ClNO5P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Phosphamidon, an organophosphate cholinesterase inhibitor, is used as an insecticide. It also disrupts cellular respiration by inhibiting ATP production. Phosphamidon has synergistic effects when combined with other chemicals, including chlorinated hydrocarbons and other organophosphorus compounds. However, aside from its toxicological impact on humans, phosphamidon also demonstrates genotoxic effects on both bacterial and mammalian cells. Phosphamidon can be used as a sample preparation agent in DNA analysis using the tetrazolium dye (MTT) and chemiluminescence method.
Phosphamidon (CAS 13171-21-6) References
- Effect of phosphamidon and obidoxime on the QT-RR relationship of isolated rat heart. | Ben-Haim, SA., et al. 1992. Pharmacol Toxicol. 70: 402-6. PMID: 1438017
- Obidoxime augments the positive inotropic effect of phosphamidon on the isolated working rat heart. | Ben-Haim, SA., et al. 1992. Pharmacol Toxicol. 71: 127-31. PMID: 1438028
- Residues of phosphamidon in rice fields. | Jebakumar, SR., et al. 1989. Environ Pollut. 61: 227-34. PMID: 15092362
- Attenuation of phosphamidon-induced oxidative stress and immune dysfunction in rats treated with N-acetylcysteine. | Suke, SG., et al. 2008. Braz J Med Biol Res. 41: 765-8. PMID: 18820765
- Determination of organophosphorous pesticide phosphamidon in environmental water with luminol chemiluminescence detection. | Li, A., et al. 2009. J AOAC Int. 92: 914-8. PMID: 19610385
- Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats. | Joshi, V., et al. 2010. Naunyn Schmiedebergs Arch Pharmacol. 382: 311-20. PMID: 20737266
- Assessment of phosphamidon-induced apoptosis in human peripheral blood mononuclear cells: protective effects of N-acetylcysteine and curcumin. | Ahmed, T., et al. 2010. J Biochem Mol Toxicol. 24: 286-92. PMID: 20979154
- Effect of progesterone on phosphamidon-induced impairment of memory and oxidative stress in rats. | Sharma, AK., et al. 2011. Hum Exp Toxicol. 30: 1626-34. PMID: 21257640
- Effect of phosphamidon on cognition and oxidative stress and its modulation by ascorbic acid and 4'-chlorodiazepam in rats. | Suke, SG., et al. 2013. Pharmacol Biochem Behav. 103: 637-42. PMID: 23128021
- Modulation of carbohydrate metabolism in the selected tissues of marine prawn, Penaeus indicus (H. Milne Edwards), under phosphamidon-induced stress. | Reddy, MS. and Rao, KV. 1988. Ecotoxicol Environ Saf. 15: 212-20. PMID: 3378538
- Rate of degradation of phosphamidon and residue values. | Voss, G. and Geissbühler, H. 1971. Residue Rev. 37: 133-52. PMID: 5094943
- Chemical and physical properties of phosphamidon. | Anliker, R. and Beriger, E. 1971. Residue Rev. 37: 1-14. PMID: 5094946
- The setting of an occupational exposure limit for phosphamidon in the workplace--a Chinese approach. | Zhuang, JG., et al. 1993. Ann Occup Hyg. 37: 89-99. PMID: 8460880
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phosphamidon, 250 mg | sc-250712 | 250 mg | $156.00 |