Perindopril t-Butylamine Salt CAS: 107133-36-8
MF: C23H43N3O5
MW: 441.60
An angiotensin-converting enzyme (ACE) inhibitor.

Perindopril t-Butylamine Salt (CAS 107133-36-8)

Perindopril t-Butylamine Salt | CAS 107133-36-8 is rated 5.0 out of 5 by 1.
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Alternate Names: Perindopril Erbumine
Application: Perindopril t-Butylamine Salt is an angiotensin-converting enzyme (ACE) inhibitor
CAS Number: 107133-36-8
Purity: ≥99%
Molecular Weight: 441.60
Molecular Formula: C23H43N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Perindopril t-Butylamine Salt is an angiotensin-converting enzyme (ACE) inhibitor. Inhibition of this enzyme prevents the formation of angiotensin II from angiotensin I, which in turn prevents vasoconstriction caused by angiotensin II.


References

Lees, K.R., et al.: Brit. J. Clin. Pharmacol., 23, 159 (1987), Morgan, T., et al.: J. Cardiovasc. Pharmacol., 10, Supp. 7, S116, (1987)

Physical State :
Solid
Solubility :
Soluble in chloroform, methanol, water (≥88 mg/ml), DMSO (>10 mg/ml), and ethanol (50 mM).
Storage :
Store at 4° C
Melting Point :
126-128° C
IC50 :
angiotensin-converting enzyme: IC50 = 1.05 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NL5999600
PubChem CID :
441313
MDL Number :
MFCD02313824
SMILES :
CCC[[email protected]@H](C(=O)OCC)N[[email protected]@H](C)C(=O)N1[[email protected]]2CCCC[[email protected]]2C[[email protected]]1C(=O)O.CC(C)(C)N

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Jawaid Jawaid, T. et al. (PubMed 26317078) performed a comparative study of neuroprotective effect of angiotensin converting enzyme (ACE) inhibitors, such as Perindopril, against scopolamine-induced memory impairments in rats. Compared to other ACE inhibitors Perindopril proved to be more effective in memory retention. -SCBT Publication Review
Date published: 2015-06-05
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