Date published: 2026-4-26

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Pentachloroanisole (CAS 1825-21-4)

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CAS Number:
1825-21-4
Molecular Weight:
280.36
Molecular Formula:
C7H3Cl5O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pentachloroanisole is a chemical compound that functions as a potent inhibitor of microbial growth. It acts by disrupting the synthesis of cellular components in microorganisms, leading to their inhibition and eventual death. At the molecular level, pentachloroanisole interferes with the function of key enzymes involved in the biosynthesis of cellular components, disrupting their normal metabolic processes. This disruption ultimately impairs the ability of microorganisms to proliferate and survive in experimental applications. By targeting specific cellular pathways, pentachloroanisole effectively hinders the growth and viability of a wide range of microorganisms, making it useful for studying microbial physiology and developing strategies for microbial control. Its mechanism of action may be particularly useful for investigating the mechanisms of microbial resistance and identifying potential targets for the development of novel antimicrobial agents.


Pentachloroanisole (CAS 1825-21-4) References

  1. Pesticides and metabolites in cassava, eucalyptus, plum and cashew leaves and roots in relation to a point source in Kibaha, Tanzania.  |  Marco, JA. and Kishimba, MA. 2006. Chemosphere. 64: 542-8. PMID: 16403548
  2. Destruction of chloroanisoles by using a hydrogen peroxide activated method and its application to remove chloroanisoles from cork stoppers.  |  Recio, E., et al. 2011. J Agric Food Chem. 59: 12589-97. PMID: 22074456
  3. Optimisation of a sensitive method based on ultrasound-assisted emulsification-microextraction for the simultaneous determination of haloanisoles and volatile phenols in wine.  |  Pizarro, C., et al. 2012. J Chromatogr A. 1244: 37-45. PMID: 22608775
  4. Different headspace solid phase microextraction--gas chromatography/mass spectrometry approaches to haloanisoles analysis in wine.  |  Jeleń, HH., et al. 2013. J Chromatogr A. 1313: 185-93. PMID: 23932370
  5. Selected current-use pesticides (CUPs) in coastal and offshore sediments of Bohai and Yellow seas.  |  Zhong, G., et al. 2015. Environ Sci Pollut Res Int. 22: 1653-61. PMID: 24584589
  6. Relative developmental toxicities of pentachloroanisole and pentachlorophenol in a zebrafish model (Danio rerio).  |  Cheng, Y., et al. 2015. Ecotoxicol Environ Saf. 112: 7-14. PMID: 25463847
  7. Legacy and currently used pesticides in the atmospheric environment of Lake Victoria, East Africa.  |  Arinaitwe, K., et al. 2016. Sci Total Environ. 543: 9-18. PMID: 26575633
  8. The trans-continental distributions of pentachlorophenol and pentachloroanisole in pine needles indicate separate origins.  |  Kylin, H., et al. 2017. Environ Pollut. 229: 688-695. PMID: 28711567
  9. Air monitoring of new and legacy POPs in the Group of Latin America and Caribbean (GRULAC) region.  |  Rauert, C., et al. 2018. Environ Pollut. 243: 1252-1262. PMID: 30268978
  10. Concentrations of POPs based wood preservatives in waste timber from demolished buildings and its recycled products in Japan.  |  Koyano, S., et al. 2019. Waste Manag. 85: 445-451. PMID: 30803600
  11. Distribution and risk assessment of hexachlorobutadiene, pentachloroanisole, and chlorobenzenes in sediment and wild fish from a region affected by industrial and agricultural activities in South China.  |  Lu, Y., et al. 2021. J Hazard Mater. 417: 126002. PMID: 33992918
  12. Cultivation-dependent and cultivation-independent investigation of O-methylated pollutant-producing bacteria in three drinking water treatment plants.  |  Tang, Y., et al. 2023. Water Res. 231: 119618. PMID: 36706470
  13. Toxicity and bioaccumulation of pentachlorophenol in broiler chickens.  |  Stedman, TM., et al. 1980. Poult Sci. 59: 1018-26. PMID: 7393838
  14. Distribution, metabolism and excretion of pentachloroanisole in the beagle dog and miniature pig.  |  Ikeda, GJ. and Sapienza, PP. 1995. Food Chem Toxicol. 33: 409-21. PMID: 7759026
  15. Toxicokinetics of pentachloroanisole in F344 rats and B6C3F1 mice.  |  Yuan, JH., et al. 1993. Xenobiotica. 23: 427-38. PMID: 8337901

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pentachloroanisole, 1 g

sc-257972
1 g
$84.00