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Palmarumycin C3 (CAS 159934-11-9)

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Alternate Names:
(1a'R,7a'S)-3',6'-Dihydroxy-1a'H-spiro[naphtho[1,8-de][1,3]dioxine-2,2'-naphtho[2,3-b]oxiren]-7'(7a'H)-one
CAS Number:
159934-11-9
Purity:
≥97%
Molecular Weight:
348.3
Molecular Formula:
C20H12O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Palmarumycin C3 is a spirodioxynaphthalene compound isolated from the endophytic fungus *Berkleasmium sp.*, which resides in palm trees. It features a unique structural framework that includes a spiro-linked dioxynaphthalene system, making it a focal point in the study of natural products with potential antioxidative properties. The compound′s primary mechanism involves acting as an inhibitor of oxidative stress by quenching reactive oxygen species (ROS), which are critical mediators of cellular damage and environmental stress responses. In research, Palmarumycin C3 is extensively used to explore the dynamics of oxidative stress in cells, particularly how oxidative balance is maintained and disrupted under various conditions. This exploration contributes to understanding cellular defense mechanisms against oxidative damage, providing insights into the natural biosynthesis of complex molecular structures. Additionally, studying Palmarumycin C3 helps delineate the pathways through which fungi produce complex molecules, enhancing our knowledge of fungal ecology and the potential for developing novel oxidative stress management strategies in both environmental and biological contexts.


Palmarumycin C3 (CAS 159934-11-9) References

  1. Natural products derived from naphthalenoid precursors by oxidative dimerization.  |  Krohn, K. 2003. Fortschr Chem Org Naturst. 85: 1-49. PMID: 12602036
  2. Modulation of k-Ras signaling by natural products.  |  Bharate, SB., et al. 2012. Curr Med Chem. 19: 2273-91. PMID: 22414109
  3. Antimicrobial and antioxidant activities and effect of 1-hexadecene addition on palmarumycin C2 and C3 yields in liquid culture of endophytic fungus Berkleasmium sp. Dzf12.  |  Mou, Y., et al. 2013. Molecules. 18: 15587-99. PMID: 24352015
  4. Biologically active metabolites from fungi, 5. Palmarumycins C1–C16 from Coniothyrium sp.: isolation, structure elucidation, and biological activity.  |  Krohn, Karsten,. 1994. Liebigs Annalen der Chemie.11 (1994):: 1099-1108.
  5. Cladospirones B to I from Sphaeropsidales sp. F‐24′ 707 by Variation of Culture Conditions.  |  Bode, Helge Björn, Martina Walker, and Axel Zeeck. 2000. European Journal of Organic Chemistry. 2000.18: 3185-3193.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Palmarumycin C3, 1 mg

sc-364123
1 mg
$163.00

Palmarumycin C3, 5 mg

sc-364123A
5 mg
$520.00