Oseltamivir phosphate CAS: 204255-11-8
MF: C16H28N2O4•H3PO4
MW: 410.40
An antiviral agent.

Oseltamivir phosphate (CAS 204255-11-8)

Oseltamivir phosphate | CAS 204255-11-8 is rated 5.0 out of 5 by 1.
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Alternate Names: (3R,4R,5S)-4-(Acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic Acid Ethyl Ester Phosphate; Oseltamir Phosphate
Application: Oseltamivir phosphate is an antiviral agent
CAS Number: 204255-11-8
Purity: ≥99%
Molecular Weight: 410.40
Molecular Formula: C16H28N2O4•H3PO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Oseltamivir Phosphate is an active (orally) inhibitor of the influenze virus neuraminidase and converted to the active acid metabolite in vivo. Also demonstrates antiviral drug capabilities.


References

Oliyai, R., et al.: Pharm. Res., 15, 1300 (1998), Kim, C.U., et al.: Med. Chem. Res., 8, 392 (1998), Hayden, F.G., et al.: N. Engl. J. Med., 341, 1336 (1999), Treanor, J.J., et al.: J. Am. Med. Assoc., 283, 1016 (2000)

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (>500 mg/ml), methanol, DMSO (2 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
Storage :
Store at -20° C
Melting Point :
197-212° C
Refractive Index :
n20D 1.50 (Predicted)
IC50 :
Influenza A virus: IC50 = 1.1 µM
pK Values :
pKa: 7.7 at 25° C in primary amine
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
78000
MDL Number :
MFCD08059548
Beilstein Registry :
8101020
SMILES :
CCC(CC)O[[email protected]@H]1C=C(C[[email protected]@H]([[email protected]]1NC(=O)C)N)C(=O)OCC.OP(=O)(O)O

Download SDS (MSDS)

Certificate of Analysis

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Oseltamivir phosphate (CAS 204255-11-8)  Product Citations

See how others have used Oseltamivir phosphate (CAS 204255-11-8). Click on the entry to view the PubMed entry .

Citations 1 to 5 of 5 total

PMID: # 28184906  Warkus, ELL. et al. 2017. Toxicol. Sci. 157: 235-245.

PMID: # 26185093  Li, J. et al. 2015. Nat Commun. 6: 7737.

PMID: # 33314123  Immunology.

PMID: # 29357434  Am. J. Physiol. Renal Physiol. F630-F642.

PMID: # 32187230  PLoS ONE. 15: e0230499.

Citations 1 to 5 of 5 total
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Rated 5 out of 5 by from Hrynyk et al Hrynyk et al. (PubMed ID 26309402) found that oseltamivir phosphate-loaded PLGA implants surgically inserted into sites of solid tumor reduce the likelihood of metastasis in a mice model of human pancreatic carcinoma. -SCBT Publication Review
Date published: 2015-04-02
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