Orotidine 5′-monophosphate trisodium salt (CAS 68244-58-6)
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Orotidine 5′-monophosphate trisodium salt is the sodium salt form of OMP, also known as orotidylic acid a precursor for uridine 5′-monophosphate (UMP) in the de novo pyrimidine biosynthetic pathway. The trisodium salt form enhances its solubility in water, making it particularly useful for various biochemical applications. OMP trisodium salt is of interest for studying enzyme kinetics and the mechanism of action of the enzyme orotidine 5′-phosphate decarboxylase, which catalyzes the decarboxylation of OMP to UMP. Furthermore, OMP trisodium salt serves as a starting material or intermediate in the synthesis of nucleotide analogs and derivatives. These compounds can be used in molecular biology and genetic engineering for probing nucleic acid structures and studying gene expression.
Orotidine 5′-monophosphate trisodium salt (CAS 68244-58-6) References
- An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organisms. | Toth, K., et al. 2009. Biochemistry. 48: 8006-13. PMID: 19618917
- Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate. | Toth, K., et al. 2010. J Am Chem Soc. 132: 7018-24. PMID: 20441167
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Orotidine 5′-monophosphate trisodium salt, 1 mg | sc-215638A | 1 mg | $459.00 | |||
Orotidine 5′-monophosphate trisodium salt, 2 mg | sc-215638B | 2 mg | $653.00 | |||
Orotidine 5′-monophosphate trisodium salt, 5 mg | sc-215638 | 5 mg | $1887.00 | |||
Orotidine 5′-monophosphate trisodium salt, 10 mg | sc-215638C | 10 mg | $1938.00 |