Date published: 2026-3-9

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Opiorphin (CAS 864084-88-8)

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CAS Number:
864084-88-8
Purity:
≥95%
Molecular Weight:
692.77
Molecular Formula:
C29H48N12O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Opiorphin belongs to the enkephalin family of peptides, this peptide has been recognized for its range of biochemical effects and its influence on various physiological processes. Its mechanism of action connected to the mu-opioid receptor and the delta-opioid receptor. Biochemists utilize Opiorphin in assays to understand its stability, degradation, and interaction with other proteins and enzymes. Opiorphin contributes to the broader field of peptide research by serving as a model for the investigation of intra- and extracellular signaling mechanisms. The compound′s role in scientific studies adds to the understanding of peptide functions and their potential implications in various biological applications.


Opiorphin (CAS 864084-88-8) References

  1. Human opiorphin: the lack of physiological dependence, tolerance to antinociceptive effects and abuse liability in laboratory mice.  |  Popik, P., et al. 2010. Behav Brain Res. 213: 88-93. PMID: 20438769
  2. Human opiorphin is a naturally occurring antidepressant acting selectively on enkephalin-dependent delta-opioid pathways.  |  Javelot, H., et al. 2010. J Physiol Pharmacol. 61: 355-62. PMID: 20610867
  3. Opiorphin increases blood pressure of conscious rats through renin-angiotensin system (RAS).  |  Fang, Y., et al. 2014. Peptides. 55: 47-51. PMID: 24486428
  4. Effects and underlying mechanisms of human opiorphin on cardiovascular activity in anesthetized rats.  |  Tian, XZ., et al. 2015. Eur J Pharmacol. 749: 32-8. PMID: 25460028
  5. Opiorphin analysis in equine plasma and urine using hydrophilic interaction LC-MS.  |  Wang, CC., et al. 2015. Bioanalysis. 7: 593-603. PMID: 25826141
  6. Transfer of opiorphin through a blood-brain barrier culture model.  |  Bocsik, A., et al. 2015. Arch Med Res. 46: 502-6. PMID: 26143971
  7. Opiorphin causes a panicolytic-like effect in rat panic models mediated by μ-opioid receptors in the dorsal periaqueductal gray.  |  Maraschin, JC., et al. 2016. Neuropharmacology. 101: 264-70. PMID: 26363194
  8. Antitumor activity of opiorphin, sialorphin and their conjugates with a peptide klaklakklaklak.  |  Kamysz, E., et al. 2016. J Pept Sci. 22: 723-730. PMID: 27862720
  9. Injectable liposomal formulations of opiorphin as a new therapeutic strategy in pain management.  |  Mennini, N., et al. 2015. Future Sci OA. 1: FSO2. PMID: 28031877
  10. Effects of human opiorphin on food intake and water intake in mice following central administration.  |  Chen, Y., et al. 2017. Neurosci Lett. 641: 62-69. PMID: 28104434
  11. Salivary opiorphin levels in anorexia nervosa: A case-control study.  |  Paszynska, E., et al. 2020. World J Biol Psychiatry. 21: 212-219. PMID: 30179071
  12. Salivary opiorphin in dental pain: A potential biomarker for dental disease.  |  Ozdogan, MS., et al. 2019. Arch Oral Biol. 99: 15-21. PMID: 30590229
  13. Effects of the adjunctive treatment of antidepressants with opiorphin on a panic-like defensive response in rats.  |  Maraschin, JC., et al. 2020. Behav Brain Res. 378: 112263. PMID: 31568834
  14. Role of opiorphin genes in prostate cancer growth and progression.  |  Mukherjee, A., et al. 2021. Future Oncol. 17: 2209-2223. PMID: 33593085

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Opiorphin, 1 mg

sc-253217
1 mg
$242.00