Molecular structure of Oleandomycin, CAS Number: 3922-90-5
Oleandomycin (CAS 3922-90-5)
See product citations (3)
Alternate Names:
Oleandomycin is also known as Amimycin.
Application:
Oleandomycin is a 16-membered macrocyclic lactone that demonstrates antimicrobial activity similar to penicillin and erythromycin.
CAS Number:
3922-90-5
Purity:
≥95%
Molecular Weight:
687.86
Molecular Formula:
C35H61NO12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oleandomycin is a 16-membered macrocyclic lactone. Its a classic macrolide antibiotic produced by strains of Streptomyces. Oleandomycin was initially developed as an antibiotic in vitro, but has since been phased out and is now usually used in combination in vitro with other antibiotics. Studies are underway to investigate the biosynthetic mechanism of Oleandomycin, development of resistance to the antibiotic activity of Oleandomycin, and the reactive enzymes involved in these processes.
Oleandomycin (CAS 3922-90-5) References
- Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin. | Shah, S., et al. 2000. J Antibiot (Tokyo). 53: 502-8. PMID: 10908114
- Analysis of erythromycin and oleandomycin residues in food by high-performance liquid chromatography with fluorometric detection. | Edder, P., et al. 2002. Food Addit Contam. 19: 232-40. PMID: 11834075
- The sensitivity of staphylococci and other wound bacteria to erythromycin, oleandomycin, and spiramycin. | LOWBURY, EJ. and HURST, L. 1959. J Clin Pathol. 12: 163-9. PMID: 13641436
- Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry. | Löffler, D. and Ternes, TA. 2003. J Chromatogr A. 1021: 133-44. PMID: 14735982
- In silico prediction of volume of distribution in human using linear and nonlinear models on a 669 compound data set. | Berellini, G., et al. 2009. J Med Chem. 52: 4488-95. PMID: 19603833
- Biosynthesis of oleandomycin by Streptomyces antibioticus: influence of nutritional conditions and development of resistance. | Vilches, C., et al. 1990. J Gen Microbiol. 136: 1447-54. PMID: 2262785
- A quantitative method for residues of macrolide antibiotics in porcine kidney by liquid chromatography/tandem mass spectrometry. | Dickson, LC., et al. 2012. J AOAC Int. 95: 567-75. PMID: 22649946
- Occurrence, spatiotemporal distribution, mass balance and ecological risks of antibiotics in subtropical shallow Lake Taihu, China. | Zhou, LJ., et al. 2016. Environ Sci Process Impacts. 18: 500-13. PMID: 27048777
- Veterinary antibiotics used in animal agriculture as NDMA precursors. | Leavey-Roback, SL., et al. 2016. Chemosphere. 164: 330-338. PMID: 27592322
- Assessment of human estrogen receptor agonistic/antagonistic effects of veterinary drugs used for livestock and farmed fish by OECD in vitro stably transfected transcriptional activation assays. | Lee, HS., et al. 2019. Toxicol In Vitro. 58: 256-263. PMID: 30742918
- Identification of emerging contaminants and their transformation products in a moving bed biofilm reactor (MBBR)-based drinking water treatment plant around River Yamuna in India. | Tak, S., et al. 2020. Environ Monit Assess. 192: 365. PMID: 32409992
- Electrospun Functional Nanofiber Membrane for Antibiotic Removal in Water: Review. | Zhao, K., et al. 2021. Polymers (Basel). 13: PMID: 33440744
- A second ABC transporter is involved in oleandomycin resistance and its secretion by Streptomyces antibioticus. | Olano, C., et al. 1995. Mol Microbiol. 16: 333-43. PMID: 7565095
- Biosynthesis of the macrolide oleandomycin by Streptomyces antibioticus. Purification and kinetic characterization of an oleandomycin glucosyltransferase. | Quirós, LM. and Salas, JA. 1995. J Biol Chem. 270: 18234-9. PMID: 7629141
- Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. | McFarland, JW., et al. 1997. J Med Chem. 40: 1340-6. PMID: 9135031
- Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis by Streptomyces antibioticus. | Quirós, LM., et al. 1998. Mol Microbiol. 28: 1177-85. PMID: 9680207
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oleandomycin, 5 mg | sc-391704 | 5 mg | $164.00 | |||
Oleandomycin, 5 mg | sc-391704-CW | 5 mg | $385.00 |