Date published: 2025-12-5

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Nigerose (CAS 497-48-3)

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Alternate Names:
laminaribiose; 3-O-α-D-Glucopyranosyl-D-glucose; Sakebiose
Application:
Nigerose is a substrate to identify, differentiate and quantify enzymes
CAS Number:
497-48-3
Purity:
≥90%
Molecular Weight:
342.30
Molecular Formula:
C12H22O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nigerose is an α(1,3) linked glucose disaccaharide used as a substrate to identify, differentiate and quantify enzymes such as nigerose phosphorylase(s) and α-glucosidase(s). Enzymes that specifically catalyze the hydrolysis or formation of α-1,3 linkages are studied for their potential applications in biotechnology and synthetic biology. It is a naturally occurring sugar derived from the partial hydrolysis of starch. Nigerose can be found in honey and various traditional fermented foods. Biologically, nigerose serves as a carbon source for certain microorganisms, playing a role in the metabolic pathways of bacteria and fungi capable of utilizing this sugar. The study of these pathways provides insights into microbial ecology.


Nigerose (CAS 497-48-3) References

  1. Discovery of nigerose phosphorylase from Clostridium phytofermentans.  |  Nihira, T., et al. 2012. Appl Microbiol Biotechnol. 93: 1513-22. PMID: 21808968
  2. Purification and partial biochemical characterization of a membrane-bound type II-like α-glucosidase from the yeast morphotype of Sporothrix schenckii.  |  Torres-Rodríguez, BI., et al. 2012. Antonie Van Leeuwenhoek. 101: 313-22. PMID: 21927828
  3. NMR characterization of saccharides in Italian honeys of different floral sources.  |  Consonni, R., et al. 2012. J Agric Food Chem. 60: 4526-34. PMID: 22509771
  4. Purification and characterization of 1,3-β-D-glucan phosphorylase from Ochromonas danica.  |  Yamamoto, Y., et al. 2013. Biosci Biotechnol Biochem. 77: 1949-54. PMID: 24018693
  5. Identification and enzymatic characterization of an endo-1,3-β-glucanase from Euglena gracilis.  |  Takeda, T., et al. 2015. Phytochemistry. 116: 21-27. PMID: 26028521
  6. LacI Transcriptional Regulatory Networks in Clostridium thermocellum DSM1313.  |  Wilson, CM., et al. 2017. Appl Environ Microbiol. 83: PMID: 28003194
  7. Chitosan-based hybrid immobilization in bienzymatic reactions and its application to the production of laminaribiose.  |  Müller, C., et al. 2017. Bioprocess Biosyst Eng. 40: 1399-1410. PMID: 28601941
  8. Effect of temperature on saccharification and oligosaccharide production efficiency in koji amazake.  |  Oguro, Y., et al. 2019. J Biosci Bioeng. 127: 570-574. PMID: 30414826
  9. Rational design of an improved transglucosylase for production of the rare sugar nigerose.  |  Franceus, J., et al. 2019. Chem Commun (Camb). 55: 4531-4533. PMID: 30924472
  10. In vitro digestibility of commercial and experimental isomalto-oligosaccharides.  |  Hu, Y., et al. 2020. Food Res Int. 134: 109250. PMID: 32517953
  11. Bacterial α-diglucoside metabolism: perspectives and potential for biotechnology and biomedicine.  |  Garcia, CA. and Gardner, JG. 2021. Appl Microbiol Biotechnol. 105: 4033-4052. PMID: 33961116
  12. Metabolism and Health Effects of Rare Sugars in a CACO-2/HepG2 Coculture Model.  |  van Laar, A., et al. 2022. Nutrients. 14: PMID: 35276968
  13. Characterization of an Unknown Region Linked to the Glycoside Hydrolase Family 17 β-1,3-Glucanase of Vibrio vulnificus Reveals a Novel Glucan-Binding Domain.  |  Kumagai, Y., et al. 2022. Mar Drugs. 20: PMID: 35447923
  14. Synthesis and evaluation of 1,5-dithialaminaribiose and -triose tetravalent constructs.  |  Ahiadorme, D., et al. 2023. Carbohydr Res. 525: 108781. PMID: 36898263

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nigerose, 5 mg

sc-286585
5 mg
$180.00

Nigerose, 10 mg

sc-286585A
10 mg
$290.00

Nigerose, 25 mg

sc-286585B
25 mg
$465.00

Nigerose, 50 mg

sc-286585C
50 mg
$775.00

Nigerose, 100 mg

sc-286585D
100 mg
$1200.00