Date published: 2026-6-6

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Nicotine-N-(4-deoxy-4,5-didehydro)-β-D-glucuronide (CAS 1040920-61-3)

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CAS Number:
1040920-61-3
Molecular Weight:
320.34
Molecular Formula:
C16H20N2O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nicotine-N-(4-deoxy-4,5-didehydro)-β-D-glucuronide is a chemical compound that is derived from nicotine, a naturally occurring alkaloid found in tobacco plants. It is formed in the body through a process called glucuronidation, where the liver adds a glucuronic acid molecule to nicotine, resulting in the formation of nicotine glucuronide. Nicotine glucuronide is a metabolite of nicotine, meaning it is a product of the body′s metabolism of nicotine. When nicotine is consumed, either through smoking or other forms of tobacco use, it undergoes various metabolic transformations in the body. One of these transformations involves the addition of a glucuronic acid molecule to nicotine, leading to the formation of nicotine glucuronide.


Nicotine-N-(4-deoxy-4,5-didehydro)-β-D-glucuronide (CAS 1040920-61-3) References

  1. Validation of a liquid chromatography-tandem mass spectrometry method for the detection of nicotine biomarkers in hair and an evaluation of wash procedures for removal of environmental nicotine.  |  Miller, EI., et al. 2011. J Anal Toxicol. 35: 321-32. PMID: 21740688
  2. Simultaneous quantification of nicotine and metabolites in rat brain by liquid chromatography-tandem mass spectrometry.  |  Vieira-Brock, PL., et al. 2011. J Chromatogr B Analyt Technol Biomed Life Sci. 879: 3465-74. PMID: 21963483
  3. Age-related differences in the disposition of nicotine and metabolites in rat brain and plasma.  |  Vieira-Brock, PL., et al. 2013. Nicotine Tob Res. 15: 1839-48. PMID: 23737496
  4. Nicotine Pharmacokinetics in Rat Brain and Blood by Simultaneous Microdialysis, Stable-Isotope Labeling, and UHPLC-HRMS: Determination of Nicotine Metabolites.  |  Xu, Y., et al. 2019. Anal Chem. 91: 2916-2922. PMID: 30657674

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nicotine-N-(4-deoxy-4,5-didehydro)-β-D-glucuronide, 1 mg

sc-219364
1 mg
$388.00