Date published: 2025-11-2

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NG 012 (CAS 141731-76-2)

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Alternate Names:
Orbuticin derivative
Application:
NG 012 is a novel form of nerve growth factor potentiator
CAS Number:
141731-76-2
Molecular Weight:
662.64
Molecular Formula:
C32H38O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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NG 012, a chemical compound, has attracted significant interest in scientific research due to its potential applications in various fields, particularly in molecular biology, biochemistry, and pharmacology. Although specific details regarding its mechanism of action may not be publicly available, researchers have explored its molecular interactions and biological activities to explain its role in cellular processes and disease pathways. Studies have focused on investigating NG 012′s impact on specific molecular targets or signaling pathways relevant to various research areas. Furthermore, researchers have utilized NG 012 as a tool compound in high-throughput screening assays or structure-activity relationship studies to identify novel drug candidates or probe biological mechanisms. Additionally, NG 012 may have found applications in chemical biology research, such as in the development of chemical probes or molecular tools to study protein function, cellular processes, or disease mechanisms. With ongoing advancements in chemical synthesis, molecular biology techniques, and drug discovery methodologies, NG 012 continues to be a subject of scientific investigation, offering potential insights into fundamental biological processes.


NG 012 (CAS 141731-76-2) References

  1. Funicone-related compounds, potentiators of antifungal miconazole activity, produced by Talaromycesflavus FKI-0076.  |  Arai, M., et al. 2002. J Antibiot (Tokyo). 55: 172-80. PMID: 12002999
  2. Occurence and bioactivities of funicone-related compounds.  |  Nicoletti, R., et al. 2009. Int J Mol Sci. 10: 1430-1444. PMID: 19468317
  3. Evaluation of LC-high-resolution FT-Orbitrap MS for the quantification of selected mycotoxins and the simultaneous screening of fungal metabolites in food.  |  Lehner, SM., et al. 2011. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 28: 1457-68. PMID: 21854354
  4. Calcarides A-E, antibacterial macrocyclic and linear polyesters from a Calcarisporium strain.  |  Silber, J., et al. 2013. Mar Drugs. 11: 3309-23. PMID: 23994907
  5. The Bioactive Secondary Metabolites from Talaromyces species.  |  Zhai, MM., et al. 2016. Nat Prod Bioprospect. 6: 1-24. PMID: 26746215
  6. New Records of Four Species Belonging to Eurotiales from Soil and Freshwater in Korea.  |  Pangging, M., et al. 2019. Mycobiology. 47: 154-164. PMID: 31448135
  7. Chemistry and Bioactivities of Secondary Metabolites from the Genus Talaromyces.  |  Lan, D. and Wu, B. 2020. Chem Biodivers. 17: e2000229. PMID: 32432837
  8. Antidepressant effects of novel positive allosteric modulators of Trk-receptor mediated signaling - a potential therapeutic concept?  |  Madjid, N., et al. 2023. Psychopharmacology (Berl). 240: 1789-1804. PMID: 37394539
  9. Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256  |  Schlingmann, G., et al. 2002. Tetrahedron. 58(34): 6825-6835.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

NG 012, 1 mg

sc-281104
1 mg
$128.00

NG 012, 5 mg

sc-281104A
5 mg
$490.00