Date published: 2026-1-19

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Neosolaniol (CAS 36519-25-2)

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Alternate Names:
8-Hydroxydiacetoxyscirpenol
CAS Number:
36519-25-2
Molecular Weight:
382.40
Molecular Formula:
C19H26O8
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Neosolaniol is a type of mycotoxin that is frequently a subject of research due to its presence in various agricultural commodities and its potential impact on plant and animal health. Studies often focus on its biosynthesis by Fusarium species and its contribution to Fusarium head blight in cereals, which can result in significant economic losses. Neosolaniol is also utilized in research investigating the mechanisms of mycotoxin-induced toxicity in eukaryotic cells, including the disruption of protein synthesis and DNA damage. Furthermore, its role in eliciting plant defense responses is another area of interest, as understanding these interactions can lead to the development of strategies to mitigate mycotoxin contamination in crops. Researchers also examine the environmental factors that influence neosolaniol production by fungi, which is for predicting and controlling mycotoxin levels in the food chain.


Neosolaniol (CAS 36519-25-2) References

  1. Metabolic pathways of trichothecenes.  |  Wu, Q., et al. 2010. Drug Metab Rev. 42: 250-67. PMID: 19678805
  2. HPLC of trichothecenes - Separation of neosolaniol, NT-1 toxin, and NT-2 toxin.  |  Schmidt, R. 1986. Mycotoxin Res. 2: 39-43. PMID: 23604835
  3. Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: an update.  |  Wu, QH., et al. 2014. Arch Toxicol. 88: 1309-26. PMID: 24894432
  4. A method of analysis for T-2 toxin and neosolaniol by UPLC-MS/MS in apple fruit inoculated with Trichothecium roseum.  |  Tang, Y., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 480-7. PMID: 25254921
  5. Role of Peptide YY3-36 and Glucose-Dependent Insulinotropic Polypeptide in Anorexia Induction by Trichothecences T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol.  |  Zhang, J., et al. 2017. Toxicol Sci. 159: 203-210. PMID: 28666375
  6. Gut satiety hormones cholecystokinin and glucagon-like Peptide-17-36 amide mediate anorexia induction by trichothecenes T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol.  |  Zhang, J., et al. 2017. Toxicol Appl Pharmacol. 335: 49-55. PMID: 28964791
  7. Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol.  |  Zhang, J., et al. 2018. Toxins (Basel). 10: PMID: 29710820
  8. Anorectic responses to T-2 toxin, HT-2 toxin, diacetoxyscirpenol and neosolaniol correspond to plasma elevations of neurotransmitters 5-hydroxytryptamine and substance P.  |  Zhang, J., et al. 2018. Ecotoxicol Environ Saf. 161: 451-458. PMID: 29909314
  9. Acetylsalicylic acid treatment reduce Fusarium rot development and neosolaniol accumulation in muskmelon fruit.  |  Xue, H., et al. 2019. Food Chem. 289: 278-284. PMID: 30955613
  10. The trichothecene neosolaniol stimulates an emetic response through neuropeptide Y2 and serotonin 3 receptors in mink.  |  Wu, Q., et al. 2021. Toxicology. 452: 152718. PMID: 33581213
  11. Trichothecenes in food and feed: Occurrence, impact on human health and their detection and management strategies.  |  Mahato, DK., et al. 2022. Toxicon. 208: 62-77. PMID: 35104534
  12. Potential Role of Individual and Combined Effects of T-2 Toxin, HT-2 Toxin and Neosolaniol on the Apoptosis of Porcine Leydig Cells.  |  Xu, J., et al. 2022. Toxins (Basel). 14: PMID: 35202172
  13. Stressful Effects of T-2 Metabolites and Defense Capability of HepG2 Cells.  |  Taroncher, M., et al. 2022. Toxins (Basel). 14: PMID: 36548737

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Neosolaniol, 5 mg

sc-250556
5 mg
$739.00