Molecular structure of Naftopidil hydrochloride, CAS Number: 57149-07-2 (free base)
Naftopidil hydrochloride (CAS 57149-07-2 (free base))
Alternate Names:
KT-611 hydrochloride
Application:
Naftopidil hydrochloride is an α1-AR adrenoceptor antagonist
CAS Number:
57149-07-2 (free base)
Purity:
≥98%
Molecular Weight:
428.96
Molecular Formula:
C24H28N2O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Naftopidil hydrochloride is an α1-AR adrenoceptor antagonist with only weak antagonism at post-junctional α2-AR receptors.
Naftopidil hydrochloride (CAS 57149-07-2 (free base)) References
- Pharmacological profile of the novel alpha-adrenoceptor antagonist KT-611 (naftopidil). | Muramatsu, I., et al. 1991. Jpn J Pharmacol. 55: 391-8. PMID: 1677438
- Radioreceptor assay for the determination of alpha 1-adrenoceptor-binding material in rat plasma following single oral administration of naftopidil. | Borbe, HO. and Peter, G. 1990. Arzneimittelforschung. 40: 253-6. PMID: 1971750
- Ethanol Dependence Abolishes Monoamine and GIRK (Kir3) Channel Inhibition of Orbitofrontal Cortex Excitability. | Nimitvilai, S., et al. 2017. Neuropsychopharmacology. 42: 1800-1812. PMID: 28139680
- Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice. | Nimitvilai, S., et al. 2018. Neuropharmacology. 137: 1-12. PMID: 29689260
- Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway. | Qian, D., et al. 2022. BMC Complement Med Ther. 22: 115. PMID: 35468773
Inhibitor of:
alpha1A-AR, and Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naftopidil hydrochloride, 10 mg | sc-203151 | 10 mg | $55.00 | |||
Naftopidil hydrochloride, 50 mg | sc-203151A | 50 mg | $175.00 |