N-tridecanoyl-L-Homserine lactone (CAS 878627-21-5)
QUICK LINKS
N-tridecanoyl-L-Homserine lactone is a signaling molecule that functions as an autoinducer in quorum sensing systems. It plays a role in regulating gene expression in bacterial populations, influencing behaviors such as biofilm formation, virulence factor production, and antibiotic resistance. This molecule interacts with specific receptors in bacterial cells, triggering a cascade of intracellular signaling events that ultimately lead to coordinated responses within the population. By modulating gene expression, N-tridecanoyl-L-Homserine lactone helps bacteria to adapt to changing environmental conditions and coordinate group behaviors. Its mechanism of action involves binding to transcriptional regulators and influencing the expression of target genes, thereby influencing the behavior of bacterial populations.
N-tridecanoyl-L-Homserine lactone (CAS 878627-21-5) References
- Specificity of acyl-homoserine lactone synthases examined by mass spectrometry. | Gould, TA., et al. 2006. J Bacteriol. 188: 773-83. PMID: 16385066
- Methylobacterium extorquens AM1 produces a novel type of acyl-homoserine lactone with a double unsaturated side chain under methylotrophic growth conditions. | Nieto Penalver, CG., et al. 2006. FEBS Lett. 580: 561-7. PMID: 16412429
- Comprehensive profiling of N-acylhomoserine lactones produced by Yersinia pseudotuberculosis using liquid chromatography coupled to hybrid quadrupole-linear ion trap mass spectrometry. | Ortori, CA., et al. 2007. Anal Bioanal Chem. 387: 497-511. PMID: 16967185
- Messing with bacterial quorum sensing. | González, JE. and Keshavan, ND. 2006. Microbiol Mol Biol Rev. 70: 859-75. PMID: 17158701
- The biology and future prospects of antivirulence therapies. | Cegelski, L., et al. 2008. Nat Rev Microbiol. 6: 17-27. PMID: 18079741
- Metabolomics analysis revealed the neuroprotective role of 2-phosphoglyceric acid in hypoxic-ischemic brain damage through GPX4/ACSL4 axis regulation. | Chen, H., et al. 2024. Eur J Pharmacol. 971: 176539. PMID: 38565342
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-tridecanoyl-L-Homserine lactone, 5 mg | sc-204812 | 5 mg | $40.00 | |||
N-tridecanoyl-L-Homserine lactone, 10 mg | sc-204812A | 10 mg | $103.00 |