Molecular structure of n-Octyl-β-D-glucopyranoside, CAS Number: 29836-26-8
n-Octyl-β-D-glucopyranoside (CAS 29836-26-8)
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Alternate Names:
n-Octyl-β-D-glucopyranoside is also known as n-Octylglucoside.
Application:
n-Octyl-β-D-glucopyranoside is a mild, non-denaturing nonionic detergent that is used for the solubilization and reconstitution of membrane-bound proteins.
CAS Number:
29836-26-8
Purity:
≥98%
Molecular Weight:
292.34
Molecular Formula:
C14H28O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
n-Octyl-β-D-glucopyranoside (OGP) is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. It has a well–defined chemical structure, small uniform micelles, and high water solubility, which make it superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.
n-Octyl-β-D-glucopyranoside (CAS 29836-26-8) References
- Reconstitution of the sarcoplasmic reticulum Ca(2+)-ATPase: mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. | Lévy, D., et al. 1992. Biochim Biophys Acta. 1107: 283-98. PMID: 1387003
- Solubilization and reconstitution of the Pseudomonas aeruginosa high affinity branched-chain amino acid transport system. | Hoshino, T., et al. 1992. J Biol Chem. 267: 21313-8. PMID: 1400443
- Purification and crystallization of the light harvesting LH1 complex from Rhodobacter sphaeroides. | Nunn, RS., et al. 1992. J Mol Biol. 228: 1259-62. PMID: 1474590
- Widespread distribution of some minor chlorophyll-protein complexes in some plants and algae. | Camm, EL. and Green, BR. 1981. Plant Physiol. 67: 1061-3. PMID: 16661784
- Reassembly of an integral oligomeric membrane protein OmpF porin in n-octyl beta-D: -glucopyranoside-lipids mixtures. | Watanabe, Y. and Inoko, Y. 2009. Protein J. 28: 66-73. PMID: 19199013
- Interaction of n-octyl β,D-glucopyranoside with giant magnetic-fluid-loaded phosphatidylcholine vesicles: direct visualization of membrane curvature fluctuations as a function of surfactant partitioning between water and lipid bilayer. | Ménager, C., et al. 2010. Langmuir. 26: 15453-63. PMID: 20825201
- Purification of octyl beta-D-glucopyranoside and re-estimation of its micellar size. | Lorber, B., et al. 1990. Biochim Biophys Acta. 1023: 254-65. PMID: 2328249
- Hydrodynamic characterization of vasoactive intestinal peptide receptors extracted from rat lung membranes in Triton X-100 and n-octyl-beta-D-glucopyranoside. | Patthi, S., et al. 1987. J Biol Chem. 262: 15740-5. PMID: 2824466
- Preparation of hemoglobin-containing liposomes using octyl glucoside and octyltetraoxyethylene. | Jopski, B., et al. 1989. Biochim Biophys Acta. 978: 79-84. PMID: 2914131
- Evaluation of Octyl-β-D-Glucopyranoside (OGP) for Cytotoxic, Hemolytic, Thrombolytic, and Antibacterial Activity. | Dinesh, M., et al. 2018. Appl Biochem Biotechnol. 185: 450-463. PMID: 29178056
- Chemoenzymatic synthesis of the pH responsive surfactant octyl β-D-glucopyranoside uronic acid. | Ngo, NTN., et al. 2020. Appl Microbiol Biotechnol. 104: 1055-1062. PMID: 31811319
- Targeting a conserved pocket (n-octyl-β-D-glucoside) on the dengue virus envelope protein by small bioactive molecule inhibitors. | Naresh, P., et al. 2022. J Biomol Struct Dyn. 40: 4866-4878. PMID: 33345726
- Solid-Supported Assembly Composed of n-Octyl-β-D-glucopyranoside and 1,2-Dioleoyl-sn-glycero-3-phosphocholine in Equilibrium with Its Ambient Aqueous Solution System Including Dispersed Assembly. | Ishiguro, R. and Kameyama, K. 2022. J Oleo Sci. 71: 223-233. PMID: 35110465
- Simple Thermodynamic Description of the Micellar-Bilayer State Transition of Assemblies Composed of n-Octyl-β-D-glucopyranoside and 1,2-Dioleolyl-sn-glycero-3-phosphocholine Dispersed in Aqueous Media or Supported on Solid Substrates. | Ishiguro, R., et al. 2022. J Oleo Sci. 71: 235-246. PMID: 35110466
- Effects of octyl beta-glucoside on insulin binding to solubilized membrane receptors. | Gould, RJ., et al. 1981. Biochemistry. 20: 6776-81. PMID: 7032581
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
n-Octyl-β-D-glucopyranoside, 500 mg | sc-281091 | 500 mg | $35.00 | |||
n-Octyl-β-D-glucopyranoside, 1 g | sc-281091A | 1 g | $55.00 | |||
n-Octyl-β-D-glucopyranoside, 5 g | sc-281091B | 5 g | $180.00 | |||
n-Octyl-β-D-glucopyranoside, 25 g | sc-281091C | 25 g | $299.00 |