n-Octyl-β-D-glucopyranoside is a non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. n-Octyl-β-D-glucopyranoside has a well–defined chemical structure, small uniform micelles, and high water solubility, which make n-Octyl-β-D-glucopyranoside superior to most other nonionic detergents for membrane solubilization. Because of the high critical micelle concentration (20-25 mM), n-Octyl-β-D-glucopyranoside has the additional advantage of being removed easily by dialysis when compared to bile salts. n-Octyl-β-D-glucopyranoside is also known as N-Octyl glucoside, OGP, OG, n-Octylglucoside, and octyl-β-D-glucopyranoside.
1. Lévy, D., et al., 1992. Reconstitution of the sarcoplasmic reticulum Ca(2+)-ATPase: mechanisms of membrane protein insertion into liposomes during reconstitution procedures involving the use of detergents. Biochimica et biophysica acta. 1107(2): 283-98. PMID: 1387003
2. Hoshino, T., et al., 1992. Solubilization and reconstitution of the Pseudomonas aeruginosa high affinity branched-chain amino acid transport system. The Journal of biological chemistry. 267(30): 21313-8. PMID: 1400443
3. Nunn, R S., et al., 1992. Purification and crystallization of the light harvesting LH1 complex from Rhodobacter sphaeroides. Journal of molecular biology. 228(4): 1259-62. PMID: 1474590
4. Lorber, B., et al., 1990. Purification of octyl beta-D-glucopyranoside and re-estimation of its micellar size. Biochimica et biophysica acta. 1023(2): 254-65. PMID: 2328249
5. Jopski, B., et al., 1989. Preparation of hemoglobin-containing liposomes using octyl glucoside and octyltetraoxyethylene. Biochimica et biophysica acta. 978(1): 79-84. PMID: 2914131
6. Gould, R J., et al., 1981. Effects of octyl beta-glucoside on insulin binding to solubilized membrane receptors. Biochemistry. 20(24): 6776-81. PMID: 7032581
7. Camm, E L., et al., 1981. Widespread distribution of some minor chlorophyll-protein complexes in some plants and algae. Plant physiology. 67(5): 1061-3. PMID: 16661784
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