N,N′-Didansyl-L-cystine (CAS 18468-46-7)
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N,N′-Didansyl-L-cystine is a compound used in various research disciplines, especially in the study of protein folding and conformational analysis. This molecule, with its two dansyl moieties attached to a cystine residue, serves as a fluorescent probe due to the dansyl groups′ ability to emit light upon excitation. Researchers utilize N,N′-Didansyl-L-cystine to investigate the presence and accessibility of thiol groups in proteins, which can provide insights into protein tertiary and quaternary structures. The compound′s properties also make it useful for studying the kinetics of thiol-disulfide exchange reactions, which are critical to understanding redox regulation in biological systems. Moreover, N,N′-Didansyl-L-cystine is employed in the development of high-performance liquid chromatography (HPLC) methods for detecting and quantifying thiol-containing compounds in complex mixtures.
N,N′-Didansyl-L-cystine (CAS 18468-46-7) References
- Surface molecular imprinting by atom transfer radical polymerization. | Wei, X., et al. 2005. Biomacromolecules. 6: 1113-21. PMID: 15762684
- Adsorption of dansylated amino acids on molecularly imprinted surfaces: a surface plasmon resonance study. | Li, X. and Husson, SM. 2006. Biosens Bioelectron. 22: 336-48. PMID: 16753292
- Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine. | Cohen, A., et al. 2007. Technol Cancer Res Treat. 6: 221-34. PMID: 17535031
- Targeting cell death in vivo in experimental traumatic brain injury by a novel molecular probe. | Reshef, A., et al. 2008. J Neurotrauma. 25: 569-80. PMID: 18447626
- Novel fluorescence molecular imaging of chemotherapy-induced intestinal apoptosis. | Levin, G., et al. 2009. J Biomed Opt. 14: 054019. PMID: 19895121
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N,N′-Didansyl-L-cystine, 100 mg | sc-215508 | 100 mg | $208.00 | |||
N,N′-Didansyl-L-cystine, 500 mg | sc-215508A | 500 mg | $791.00 |