Molecular structure of N-(NBD-Aminolauroyl)safingol, CAS Number: 474943-07-2
N-(NBD-Aminolauroyl)safingol (CAS 474943-07-2)
Alternate Names:
N-[6-[(7-Nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-L-threo-sphinganine; NBD-C12-Safingol
Application:
N-(NBD-Aminolauroyl)safingol is a fluorescent probe for labeling of membranous fatty acid phospholipids; ex:460nm/em:534nm
CAS Number:
474943-07-2
Purity:
≥98%
Molecular Weight:
661.92
Molecular Formula:
C36H63N5O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-(NBD-Aminolauroyl)safingol, also designated C12-NBD-safingol is a fluorescent probe for labeling of membranous fatty acid phospholipids. NBD group excitation: 460 nm; emission: 534 nm.
N-(NBD-Aminolauroyl)safingol (CAS 474943-07-2) References
- Preparation of fluorescence-labeled GM1 and sphingomyelin by the reverse hydrolysis reaction of sphingolipid ceramide N-deacylase as substrates for assay of sphingolipid-degrading enzymes and for detection of sphingolipid-binding proteins. | Nakagawa, T., et al. 1999. J Biochem. 126: 604-11. PMID: 10467178
- Sorting of sphingolipids in the endocytic pathway of HT29 cells. | Kok, JW., et al. 1991. J Cell Biol. 114: 231-9. PMID: 2071671
- Normal- and reverse-phase HPLC separations of fluorescent (NBD) lipids. | Martin, OC. and Pagano, RE. 1986. Anal Biochem. 159: 101-8. PMID: 3812987
- Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C. | Sachs, CW., et al. 1995. J Biol Chem. 270: 26639-48. PMID: 7592889
- Loss of Drs2p does not abolish transfer of fluorescence-labeled phospholipids across the plasma membrane of Saccharomyces cerevisiae. | Siegmund, A., et al. 1998. J Biol Chem. 273: 34399-405. PMID: 9852106
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(NBD-Aminolauroyl)safingol, 50 µg | sc-301251 | 50 µg | $200.00 |