Date published: 2026-5-17

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N-Desmethyl Asenapine Hydrochloride (CAS 1170701-78-6)

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Application:
N-Desmethyl Asenapine Hydrochloride is An Asenapine metabolite
CAS Number:
1170701-78-6
Purity:
98%
Molecular Weight:
308.20
Molecular Formula:
C16H14ClNO•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Desmethyl Asenapine is a compound that functions as a potent antagonist at various neurotransmitter receptors, including dopamine, serotonin, and adrenergic receptors. It exerts its mechanism of action by binding to these receptors and modulating their activity, leading to downstream effects on neurotransmission and signaling pathways. N-Desmethyl Asenapine interacts with the receptors in a manner that inhibits their activation by endogenous neurotransmitters, thereby altering the balance of neurotransmission in the central nervous system. Through its interactions with these receptors, N-Desmethyl Asenapine may influence neuronal excitability, synaptic transmission, and ultimately, various physiological and behavioral processes. Its ability to modulate neurotransmitter receptor activity may be investigating the molecular and cellular mechanisms underlying neurological and psychiatric disorders, as well as for elucidating the complex interplay of neurotransmitter systems in the brain.


N-Desmethyl Asenapine Hydrochloride (CAS 1170701-78-6) References

  1. Comparative susceptibilities of hybrid mice to four mammary tumor viruses from two mouse strains.  |  Moore, DH., et al. 1978. Cancer Res. 38: 3871-8. PMID: 212182
  2. Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS.  |  Patel, NP., et al. 2018. J Pharm Anal. 8: 341-347. PMID: 30345149

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Desmethyl Asenapine Hydrochloride, 1 mg

sc-212182
1 mg
$360.00