N-Carbamoyl-DL-aspartic acid (CAS 923-37-5)

N-Carbamoyl-DL-aspartic acid, also known as N-Carbamoylaspartate, is an intermediate compound in the urea cycle and nucleotide biosynthesis pathways, playing a pivotal role in the metabolic framework of various organisms. This compound is synthesized through the condensation of carbamoyl phosphate and aspartate, a reaction catalyzed by the enzyme aspartate transcarbamoylase. This process is critical in the synthesis of pyrimidines, where N-Carbamoyl-DL-aspartic acid acts as a precursor for the production of cytosine, thymine, and uracil, fundamental components of the genetic material in cells. In research, N-Carbamoyl-DL-aspartic acid is utilized to study enzymatic activities within the urea and pyrimidine biosynthesis pathways, offering insights into genetic regulation, enzyme kinetics, and pathway optimization. Its role extends to the exploration of metabolic diseases related to nucleotide synthesis dysregulation, serving as a tool in dissecting the complex interactions within cellular metabolic networks.